Researchers explore how changes in the patterns of activity in the basolateral amygdala contribute to negative emotions such as fear, anxiety, and depression.
Neurons in the basolateral amygdala allow rats to respond to and recall ethological stimuli.
Brain mapping study reveals memory engrams are widely distributed throughout the brain, including among regions not previously realized.
A ventral tegmental area dopamine neuron circuit that projects to the basolateral amygdala selectively controls anxiety-like behaviors, but not depression-like behaviors.
Increased levels of dopamine release in the basolateral amygdala as a result of stressful situations during infancy could lead to lasting behavioral issues and social difficulties, a new study reports.
Researchers have identified a pre-programmed neural circuit in the basolateral amygdala of mice that processes both positive and negative stimuli.
Allopregnanolone, a neuroactive steroid used in the treatment of postpartum depression, alters neural communication in the basolateral amygdala, an area of the brain associated with emotion and mood regulation. The drug may alter the network associated with chronic stress, which may explain its persistent antidepressant effect.
Study reveals how two neural circuits dictate the choice between social approach and avoidance. The network connecting the infralimbic cortex to the basolateral amygdala (BLA) impairs social behavior if there is a decrease in neural activity. Another network connecting the prelimbic cortex to the BLA similarly impairs social behavior if the neural activity is increased.
Corticotropin-releasing factor and neuropeptide Y work in synchronized opposition to each other to remodel and rewire neurons in the amygdala as a response to stress. The process, researchers say, can be manually reversed to help relieve anxiety.