BACE1 Archives - Neuroscience News

Periodontal Disease Bacteria May Kick Start Alzheimer’s

Neuroscience NewsOctober 4, 2018

A new mouse study reveals long term exposure to bacteria associated with periodontal disease causes neuroinflammation and neurodegeneration, leading to similar effects of Alzheimer's disease. Researchers report periodontal disease may be an initiator of Alzheimer's.... Read More...

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a brain with a drawing of a viral vector on top

Viral Connection to Alzheimer’s: Herpes Virus Implicated in Alzheimer’s Disease

Neuroscience NewsJune 21, 2018

Researchers provide evidence that certain species of human herpesvirus contribute to the development of Alzheimer's disease. The study reports high levels of human herpesvirus 6A and 7 were found in brain samples showing signs of Alzheimer's neuropathology. The findings offer hints of the viral mechanisms that could trigger or exacerbate AD.... Read More...

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Overlapping Mechanisms in HIV Cognitive Disorders and Alzheimer’s

Neuroscience NewsApril 9, 2018

A new Journal of Neuroscience study reports elevated levels of BACE1, an enzyme associated with neuronal damage in Alzheimer's disease, were identified in postmortem brain samples of those with HIV.... Read More...

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Researchers Successfully Reverse Alzheimer’s Disease: Mouse Study

Neuroscience NewsFebruary 14, 2018

Depleting BACE1 completely reverses the formation of amyloid plaques and improves cognitive function in mouse models of Alzheimer's disease, researchers report.... Read More...

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Steering an Enzyme’s ‘Scissors’ Shows Potential for Stopping Alzheimer’s

Neuroscience NewsJuly 19, 2017

Researchers at UBC believe they have identified a method that could help stop Alzheimer's disease in its tracks. ... Read More...

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Alzheimer’s Roots May Extend Back As Far As the Womb

Neuroscience NewsJanuary 27, 2017

A lack of vitamin A during pregnancy or shortly after birth may facilitate Alzheimer's disease later in life, a new study reports.... Read More...

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A Link Between HIV Treatment and Neurodegeneration

Neuroscience NewsDecember 16, 2016

Researchers discovered some protease inhibitors used to treat HIV can lead to the production of the peptide amyloid beta.... Read More...

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A Potential Driver of Age and Alzheimer’s Related Memory Loss

Neuroscience NewsDecember 10, 2016

A new study reports reduced levels of Rheb result in memory loss in animal models of dementia.... Read More...

FeaturedGeneticsNeurology5 min read

Image shows brain cells from a mouse cortex.

Alzheimer’s Could be Treated With Gene Therapy: Mouse Study

Neuroscience NewsOctober 10, 2016

Researchers report they have successfully prevented the development of Alzheimer's in mice by using gene therapy delivered by a virus to the brain.... Read More...

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Long Term Use of Anticholinergic Drugs Increases Alzheimer’s Risk

Neuroscience NewsJune 22, 2016

Study reveals long term use of anticholinergic drugs, such as those used to treat allergies, can increase the risk of developing Alzheimer's disease later in life.... Read More...

FeaturedNeurology5 min read