A class of drugs called BACE1 inhibitors, originally designed to treat Alzheimer's disease, shows potential for the treatment of glioblastoma brain cancer.
Researchers have identified a molecular mechanism that disrupts the flow of enzymes in axons, results in the accumulation of amyloid plaques.
Researchers report a new drug being developed to treat stroke patients may also have neuroprotective properties against Alzheimer's disease.
A new mouse study reveals long term exposure to bacteria associated with periodontal disease causes neuroinflammation and neurodegeneration, leading to similar effects of Alzheimer's disease. Researchers report periodontal disease may be an initiator of Alzheimer's.
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Researchers provide evidence that certain species of human herpesvirus contribute to the development of Alzheimer's disease. The study reports high levels of human herpesvirus 6A and 7 were found in brain samples showing signs of Alzheimer's neuropathology. The findings offer hints of the viral mechanisms that could trigger or exacerbate AD.
A new Journal of Neuroscience study reports elevated levels of BACE1, an enzyme associated with neuronal damage in Alzheimer's disease, were identified in postmortem brain samples of those with HIV.
Depleting BACE1 completely reverses the formation of amyloid plaques and improves cognitive function in mouse models of Alzheimer's disease, researchers report.
Researchers at UBC believe they have identified a method that could help stop Alzheimer's disease in its tracks.
A lack of vitamin A during pregnancy or shortly after birth may facilitate Alzheimer's disease later in life, a new study reports.
Researchers discovered some protease inhibitors used to treat HIV can lead to the production of the peptide amyloid beta.
A new study reports reduced levels of Rheb result in memory loss in animal models of dementia.
Researchers report they have successfully prevented the development of Alzheimer's in mice by using gene therapy delivered by a virus to the brain.
