Study reveals axon density is lower than previously believed between distant regions of the brain.
Rare variants of the autism-associated ANK2 gene alter the architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.
Harnessing the power of "dancing molecules", researchers have developed a new injectable therapy that repairs tissue damage and reverses paralysis in mouse models. Within four weeks of receiving the injection, paralyzed mice regained the ability to walk.
Neuroimaging study revealed a significant number of professional rugby players had white matter abnormalities and abnormal changes to white matter volume over time.
Axonal swelling in the Purkinje cells of mice had no detrimental impact on firing rate or the speed at which axons transmit signals. At peak firing rate, axons with swellings were less likely to fail than those without.
At the site of injury, nerves release a protein called CXCL12 which attracts growing nerve fibers and keeps them trapped in place. This prevents the nerve fibers from growing in the correct direction to bridge the injury site.
A new map of the basal ganglia provides a blueprint of the structure of the brain region and reveals a new level of influence connected to this area.
A newly developed hydrogel scaffold with regularly spaced pores assists in spinal cell growth and neuron regeneration following spinal cord injury.
Glial cells not only control the speed of nerve conduction, but they also influence the precision of signal transduction.
A preclinical study reports Schwann cells assist injured axons by releasing protective sugars. The findings have positive implications for the treatment of neurodegenerative diseases like ALS.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.