FeaturedNeuroscience·February 3, 2020·3 min readBirth timing may affect brain developmentEarly birth prompted apoptosis to begin a day early, but delaying the birth did not alter when cell death began to occur. The study suggests birth time has an important and previously unrecognized effect on brain development.Read More
FeaturedGeneticsNeurologyNeuroscience·January 15, 2020·3 min readInflammation a “game changer” as cellular death dance discoveredTNFR1 receptors arrange themselves into clusters, joining together trimers and making oligomers that create a pro-inflammatory response observed in a variety of diseases.Read More
FeaturedNeurologyNeuroscience·December 9, 2019·2 min readEating more ketones may fight against Alzheimer’s diseaseIncreasing SIRT3 levels with a ketone rich diet may help protect GABAergic interneurons and delay the onset of Alzheimer's disease.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·September 13, 2019·4 min readDiscovery concerning the nervous system overturns a previous theoryRather than having an equal chance of survival, cell death appears to be controlled by a mechanism that filters our the less fit cells.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·September 4, 2019·4 min readNew insight into motor neuron death mechanisms could be a step toward ALS treatmentWhen a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered.Read More
FeaturedNeurologyNeuroscience·August 29, 2019·4 min readLack of oxygen doesn’t kill infant brain cells, as previously thoughtA lack of oxygen as a result of preterm birth does not cause hippocampal neurons to die but does impair hippocampal development. Hypoxia causes hippocampal cells to fail to mature normally, causing a reduction in long-term potentiation and impaired learning.Read More
FeaturedNeuroscience·August 22, 2019·2 min readCell suicide could hold key for brain health and food securityA new study into human and plant cell apoptosis could provide new avenues for the development of treatments for neurodegenerative diseases, and help develop disease-resistant plants.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience ArticlesPsychology·August 9, 2019·3 min readHow chronic stress causes brain damageChronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.Read More
FeaturedGeneticsNeuroscienceVisual Neuroscience·July 8, 2019·3 min readRetina restructures itself after cell deathGene therapy can restore the structure of the retina and regain normal light responses.Read More
FeaturedNeuroscience·June 24, 2019·3 min readCertain cells secrete a substance in the brain that protects neuronsVascular cell loss results in neuron loss, researchers report. However, pericytes secrete a substance that helps protect neurons, even when vascular cell degeneration begins to occur.Read More
FeaturedNeurologyNeuroscience·April 10, 2019·5 min readExperimental PET scan detects abnormal tau protein in brains of living former NFL playersPET imaging of former NFL players who exhibited cognitive decline and psychiatric symptoms linked to CTE showed higher levels of tau in areas of the brain associated with the neurodegenerative disease.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·April 9, 2019·4 min readCell death may be triggered by ‘hit-and-run’ interactionTwo different parts to the BAX protein can bind to BH3-only, and these sites function at different stages of BAX activation. When BH3-only binds to one of the regions, BAX becomes able to damage mitochondria.Read More