Findings could have broad therapeutic potential for many neurodegenerative diseases. Degeneration of the axon and synapse, the slender projection through...
Researchers visualize the molecular changes in a critical cell death protein that force cells to die. Defects in cell death have been linked to the development of diseases such as cancer and neurodegenerative conditions.
Researchers have discovered a way in which the body can remove injured axons. They also identified a potential target for new drugs which could prevent the inappropriate loss of axons, as well as maintain nerve function.
Researchers have discovered some surprising insights about the process of axonal pruning. The findings could provide clues about the processes underlying some neurological disorders such as autism and schizophrenia.
Using laboratory mice, researchers show anesthesia's neurotoxic effects depend upon the age of the neurons in the brain and not the age of the animal undergoing anesthesia.
A new study explores the connection between mechanical ventilation and hippocampal damage in ICU patients.
For those with moderate-to-severe TBI, atrophy may be countered by participating in environmental enrichment, a new study suggests.
Researchers find the amino acid, BMAA, can be inserted into neuroproteins. This causes them to misfold and aggregate. BMAA has been detected in the brains of those with ALS.
Using transgenic mice, researchers find a lack of autophagy in neurons prevents the secretion of amyloid beta and the formation of β-amyloid plaques in the brain.
Axon pruning becomes reactivated in neurodegenerative diseases, a new study finds.