A new mouse study finds APOE genes, commonly associated with Alzheimer's disease, impairs the development of new neurons in areas of the brain associated with memory. Read More
A new study has linked the APOE4 gene to mental health issues some people face following TBI. Researchers report people with the APOE4 gene had significantly higher scores for depression, PTSD and anxiety following TBI than those without the genetic variant. Read More
According to researchers, Alzheimer's disease may be more prevalent in women, not simply because they live longer on average, but due to the APOE E4 gene. Researchers found the APOE association was greater for women in the Tau pathway than in men. However, there was no difference between APOE expression in the amyloid pathway in women compared to men. Read More
University of Cambridge researchers report cholesterol may play a role in the onset of Alzheimer's disease. Researchers discovered cholesterol can trigger amyloid beta to aggregate, which can lead to neuron death. Read More
A new study reveals sleep deprivation can lead to an immediate increase in amyloid beta. Read More
Researchers from WUSTL have identified a compound that targets APOE in mouse brains and which protects against Alzheimer's disease. The APOE4 genetic variant increases the risk of people developing Alzheimer's disease. The findings offer new possible avenues of treating the disease in humans. Read More
Researchers have implicated TOMM40, a gene adjacent to APOE on chromosome 19, in the development of Alzheimer's disease. TOMM40, researchers report, plays a significant role in the decline of verbal learning after the age of 60. Read More
A new study links sleep problems with increased biomarkers for Alzheimer's disease. Researchers discovered those who report low sleep quality, daytime sleepiness and other sleep problems had elevated levels of Alzheimer's related biomarkers in their spinal fluid than those who reported no sleep problems. However, no abnormalities were found in the spinal fluid of people with obstructive sleep apnea. Read More
Researchers have identified a genetic variant that can accelerate normal brain aging in older people by up to 12 years. Read More
Researchers report older women living in areas with fine particulate matter exceeding the EPA's standard are at significantly higher risk of developing dementia. Read More
Researchers report testing both the cognitive and olfactory abilities in people could help identify those at risk for developing Alzheimer's disease. Read More
Researchers report mice can retain their memories and ability to learn when almost all ApoE is removed from the brain but kept present in the liver to filter cholesterol. Read More
