Young adults with the Alzheimer's associated ApoE gene had differences in brain activity when presented with memory tasks. Read More
Carriers of one copy of the longevity associated klotho gene reduces Alzheimer's risks by 30% for those with genetic risk factors for the neurodegenerative disease. Read More
Frequent exercise, such as walking, swimming, and dancing, was associated with less brain shrinkage in older adults. The effect of exercise in older people was equal to four fewer years of brain aging. Read More
Cognitive performance may predict the progression from normal to abnormal levels of Alzheimer's associated amyloid-beta. Read More
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS), two atypical parkinsonian syndromes, may be twice as common as previously believed, researchers report. Read More
People with a genetic predisposition for Alzheimer's disease may exhibit changes in memory up-to four decades before the typical age of dementia onset. Read More
Stimulating mouse neurons in a dish lead to a build-up to fatty acids and lipid particle release. Astrocytes engulfed the particles and increased genetic activity associated with detoxification. Read More
Mouse models and human brain tissue studies reveal microglia react to amyloid beta earlier in older females. Findings may provide avenues for the development of new drugs to help treat the neurodegenerative disease. Read More
LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone. Read More
A new study reveals a novel genetic risk loci for Alzheimer's disease. Using single cell gene expression patterns, researchers found genetic changes are expressed in microglia cells. The mutations are associated with an increased risk of Alzheimer's disease. Read More
Researchers report therapeutic activation of the TREM2 gene during the early stages of Alzheimer's disease may help to counteract the formation of amyloid beta protein aggregates. Read More
Researchers have identified specific points on chromosome 11 that increase the risks of developing both cardiovascular disease and Alzheimer's. The study reports managing cholesterol and triglyceride levels could help to reduce Alzheimer's risk. Read More
