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Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 19, 2019·5 min read

People with family history of Alzheimer’s disease may show memory changes four decades before typical age of onset

People with a genetic predisposition for Alzheimer's disease may exhibit changes in memory up-to four decades before the typical age of dementia onset.

Featured Neurology Neuroscience

·June 2, 2019·2 min read

Astrocytes protect neurons from toxic buildup

Stimulating mouse neurons in a dish lead to a build-up to fatty acids and lipid particle release. Astrocytes engulfed the particles and increased genetic activity associated with detoxification.

Featured Neurology Neuroscience Open Neuroscience Articles

·April 30, 2019·4 min read

Do microglia hold the key to stop Alzheimer’s disease?

Mouse models and human brain tissue studies reveal microglia react to amyloid beta earlier in older females. Findings may provide avenues for the development of new drugs to help treat the neurodegenerative disease.

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Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 30, 2019·5 min read

When is Alzheimer’s not Alzheimer’s? Researchers characterize a different form of dementia

LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone.

Featured Genetics Neurology Neuroscience

·January 8, 2019·4 min read

New Genetic Risk Factor for Alzheimer’s Disease

A new study reveals a novel genetic risk loci for Alzheimer's disease. Using single cell gene expression patterns, researchers found genetic changes are expressed in microglia cells. The mutations are associated with an increased risk of Alzheimer's disease.

Featured Genetics Neurology

·January 8, 2019·4 min read

Defective Immune Cells in Brain May Cause Alzheimer’s

Researchers report therapeutic activation of the TREM2 gene during the early stages of Alzheimer's disease may help to counteract the formation of amyloid beta protein aggregates.

a brain linked to the heart by a DNA strand

Featured Genetics Neurology Neuroscience

·November 12, 2018·5 min read

Alzheimer’s Genetically Linked to Cardiovascular Disease

Researchers have identified specific points on chromosome 11 that increase the risks of developing both cardiovascular disease and Alzheimer's. The study reports managing cholesterol and triglyceride levels could help to reduce Alzheimer's risk.

Featured Genetics Neurology Neuroscience

·July 30, 2018·2 min read

Alzheimer’s Risk Gene Impairs Neurogenesis: Mouse Study

A new mouse study finds APOE genes, commonly associated with Alzheimer's disease, impairs the development of new neurons in areas of the brain associated with memory.

Featured Neurology Psychology

·May 14, 2018·5 min read

Gene Variant May Increase Psychiatric Risk After TBI

A new study has linked the APOE4 gene to mental health issues some people face following TBI. Researchers report people with the APOE4 gene had significantly higher scores for depression, PTSD and anxiety following TBI than those without the genetic variant.

Featured Genetics Neurology Neuroscience Videos

·May 9, 2018·6 min read

Study Provides Robust Evidence of Sex Differences with Alzheimer’s Gene

According to researchers, Alzheimer's disease may be more prevalent in women, not simply because they live longer on average, but due to the APOE E4 gene. Researchers found the APOE association was greater for women in the Tau pathway than in men. However, there was no difference between APOE expression in the amyloid pathway in women compared to men.

Featured Neurology Neuroscience

·May 7, 2018·4 min read

Brain Cholesterol Linked to Increased Alzheimer’s Risk

University of Cambridge researchers report cholesterol may play a role in the onset of Alzheimer's disease. Researchers discovered cholesterol can trigger amyloid beta to aggregate, which can lead to neuron death.