New therapeutic target for depression identified
A fragment of the neuropeptide Galanin appears to play a role in anhedonia in mouse models of depression. Galanin could be a potential target for the treatment of depression.... Read More...
anhedonia
Inflammation induces anhedonia in women but not men
Inflammation appears to reduce reward response in females. Reduced activity in the brain's reward system is a key component of anhedonia, the loss of enjoyment in activities, a core feature of depression. The findings may explain why depression is more prevalent in women than in men.... Read More...
Differences in brain activity in children with anhedonia
Using fMRI to examine the brains of children while resting, researchers discover anhedonia is associated with hyperconnectivity between the cingulo-opercular network and ventral striatum.... Read More...
New Insights Into Loss of Pleasure in Depression
A new study reveals a brain region that contributes to anhedonia, the loss of pleasure, in those with depression. The study also shows how ketamine acts on this brain region, explaining why the drug appears to be so effective at treating anhedonia.... Read More...
Personality and Mood Affect Brain Response to Personal Choice
Researchers report personality traits and psychological health impact how we value personal control when making decisions. The study reports brain activity in the motivation system is dampened in those with passive personalities and depression when we receive rewards that we have earned or feel in personal control of situations.... Read More...
Could Cognitive Interventions be Useful in Treating Depression?
Researchers report cognitive bias modification may be a useful method for treating depression.... Read More...
People with Anhedonia Do Experience Pleasure, Just Not As Often
It is possible for those with anhedonia to enjoy experiences and feel pleasure, however, those with the disorder find it hard to maintain their positive emotions, a new study reports.... Read More...
Many Different Types of Anxiety and Depression Exist
Stanford researchers have identified five new categories of specific symptoms and brain area activation that can be applied to the diagnosis of anxiety and depression in a more specific manner.... Read More...
Sex, Drugs, and Rock & Roll Chemistry in the Brain
Using a drug used to help treat addiction, researcher report exposing people to their favorite songs no longer elicit feelings of pleasure.... Read More...
Not Feeling the Music? Lack of Joy From Music Linked to Brain Disconnection
People with musical anhedonia have reduced connectivity between brain areas associated with reward and sound processing, a new study reports.... Read More...
How Do the Brains of People Who Don’t Like Music Work?
Researchers explain the neural mechanisms behind a person's lack of sensitivity to music.... Read More...
Brain Structure That Tracks Negative Events Backfires in Depression
In depressed people, the habenula functions abnormally, a new study reports.... Read More...