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          Alzheimer’s disease

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain
          FeaturedNeurologyNeuroscience
          ·August 14, 2026·4 min read

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          Researchers discovered that the youth-associated protein TIMP2 restores healthy immune function in the aging brain by rejuvenating microglia.
          Read More
          Alternative graphical abstract is shown.
          FeaturedNeurologyNeuroscience
          ·August 11, 2026·3 min read

          Study of Brain Immune Cells Reveals New Clues to Alzheimer’s Disease Progression

          Researchers have mapped over 830,000 brain immune cells, revealing a protective subtype of microglia that increases with Alzheimer’s progression. This subtype aids in clearing harmful material via the TREM2 pathway. The findings suggest new therapeutic targets focused on bolstering the brain's immune response rather than solely targeting amyloid plaques.
          Read More
          This shows a marmoset.
          FeaturedGeneticsNeurologyNeuroscience
          ·August 6, 2026·9 min read

          Marmoset Genome Unlocks Alzheimer’s Insights

          A new study delivers the first gapless marmoset genome, mapping 76 Alzheimer's-linked genes and novel PSEN1 variants.
          Read More
          This shows mitochondria.
          FeaturedGeneticsNeurologyNeuroscience
          ·August 6, 2026·12 min read

          Tau Infiltrates Mitochondria to Drive Alzheimer’s

          Hyperphosphorylated tau invades mitochondria and triggers reverse electron transport, opening a novel target for treating Alzheimer's disease and tauopathies.
          Read More
          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·August 4, 2026·9 min read

          Phase 1 Trial Validates Anti-PD-L1 Antibody for Alzheimer’s

          IBC-Ab002, an anti-PD-L1 immunotherapy targeting systemic immune aging, is safe and reduces markers of neuronal damage in Alzheimer's patients.
          Read More
          This shows a brain model.
          FeaturedNeurologyNeuroscience
          ·August 4, 2026·8 min read

          3D Human Brain Tissue Model Replicates Alzheimer’s Pathology

          Researchers developed a 3D human brain tissue model incorporating neurons, astrocytes, and microglia that replicates Alzheimer's plaque clearance, paving the way for automated high-throughput drug testing.
          Read More
          This shows a brain map.
          FeaturedNeurologyNeuroscience
          ·August 3, 2026·10 min read

          AI Maps Regional Brain Age and Alzheimer’s Risk

          A new study uses AI voxel mapping to highlight regional brain age acceleration in Alzheimer's disease.
          Read More
          This shows a brain surrounded by mitochondria.
          FeaturedGeneticsNeurologyNeuroscience
          ·July 31, 2026·6 min read

          Mitochondrial Plaques in Alzheimer’s Brains Discovered

          Researchers identified mitochondrial plaques, an intracellular form of pathology that forms early in Alzheimer's disease and offers a new target for treatment.
          Read More
          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·July 27, 2026·8 min read

          Vagus Nerve Gut Signals Drive Spatial Memory

          A new study reveals that the vagus nerve transmits gut nutrient signals to the hippocampus, boosting acetylcholine release and spatial memory.
          Read More
          This shows DNA and a head.
          FeaturedGeneticsNeurologyNeuroscience
          ·July 25, 2026·8 min read

          Alzheimer Genetic Risk Scores Do Not Explain SuperAging

          A new study demonstrates that SuperAgers cannot be distinguished from cognitively average peers by APOE status or polygenic risk scores.
          Read More
          This shows a neuron.
          FeaturedGeneticsNeurologyNeuroscience
          ·July 23, 2026·10 min read

          3D Genome Disruption in Alzheimer’s Disease

          A new study shows that 3D genome architecture is altered in prefrontal cortex cells of individuals with Alzheimer's disease.
          Read More
          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·July 21, 2026·8 min read

          Study Maps Accelerated Brain Aging Signatures Across 9 Conditions

          Measuring Predictive Age Difference (PAD), the team found that Alzheimer’s disease and mild cognitive impairment showed the highest accelerated brain aging, followed by psychiatric disorders and substance addiction.
          Read More
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          • How Severe Illness During Pregnancy Alters Fetal Brain Development
          • Aging Brains Maintain Robust Language Networks Despite Cognitive Decline
          • Youth Protein TIMP2 Restores Immune Function in the Aging Brain
          • Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help
          • Study of Brain Immune Cells Reveals New Clues to Alzheimer’s Disease Progression
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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