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Alzheimer’s disease

·September 2, 2025·5 min read

3-Minute Brainwave Test Detects Alzheimer’s Years Before Symptoms

A team of researchers has developed a simple three-minute brainwave test called Fastball EEG that can detect early signs of memory impairment linked to Alzheimer’s disease. Unlike traditional memory tests, it is passive and requires no active participation, making it more objective and accessible.

Featured Genetics Neurology Neuroscience

·September 2, 2025·9 min read

Alzheimer’s Linked to Epigenomic Breakdown, Not Just Plaques

A new large-scale study shows that Alzheimer’s disease is marked by the erosion of epigenomic control, where brain cells lose the ability to maintain stable gene expression. Using a multi-region atlas of 3.5 million cells, researchers found that vulnerable cells in key memory regions such as the hippocampus suffer breakdowns in nuclear compartmentalization and lose their “epigenomic information.”

Featured Neurology Neuroscience

·August 29, 2025·5 min read

Gut Immune Cells Found Migrating to Alzheimer’s Brain

Researchers have uncovered a surprising link between gut immune cells and the brain in Alzheimer’s disease. In mice, antibody-producing B cells that normally reside in the gut were found migrating into brain border regions, influenced by chemokine signals from inflammatory brain cells.

Featured Neurology Neuroscience Visual Neuroscience

·August 28, 2025·6 min read

Brain Rewiring Patterns May Predict Alzheimer’s Years in Advance

Researchers have discovered that people with Alzheimer’s show unusually high neural flexibility—the constant reorganizing of brain networks—even while resting. In a large study of older adults, higher neural flexibility in the visual network predicted which healthy participants would later develop dementia.

This shows a brain surrounded by proteins in a snow globe.

Featured Genetics Neurology Neuroscience

·August 26, 2025·6 min read

Blocking a Brain “Death Complex” Slows Alzheimer’s

Scientists have discovered that a toxic complex formed between NMDA receptors and TRPM4 channels drives neuron death in Alzheimer’s disease. Using a novel molecule called FP802, researchers were able to break apart this “death complex” in mice, preventing cognitive decline, synapse loss, and mitochondrial damage.

Featured Neurology Neuroscience Visual Neuroscience

·August 26, 2025·6 min read

Eye Exams Could Spot Alzheimer’s Decades Before Symptoms Appear

Eye exams could help detect Alzheimer’s disease years before symptoms arise. By studying mice with a common genetic mutation, researchers found abnormal changes in retinal blood vessels that paralleled brain changes linked to dementia risk.

Featured Neurology Neuroscience

·August 26, 2025·8 min read

Blood Flow Dynamics Reveal Early Signs of Alzheimer’s Disease

Researchers have developed a non-invasive diagnostic tool for Alzheimer’s disease that measures how the brain regulates blood flow and oxygen. Called the Cerebrovascular Dynamics Index (CDI), it uses Doppler ultrasound and near-infrared spectroscopy to assess vascular responsiveness.

This shows an older man walking on a golden path, surrounded by networks of people.

Featured Neurology Neuroscience

·August 25, 2025·6 min read

Having a Purpose in Life Linked to Lower Dementia Risk

A new study of over 13,000 adults found that having a strong sense of purpose in life is linked to a reduced risk of dementia. Those with higher purpose were 28% less likely to develop cognitive impairment, even when accounting for genetic risk and other factors.

This shows a neuron attached to a flower, as though to imply the olfactory implications associated with Alzheimer's.

Featured Neurology Neuroscience

·August 17, 2025·4 min read

Immune Attack on Smell Pathways May Signal Early Alzheimer’s

A fading sense of smell may be one of the earliest warning signs of Alzheimer’s disease, and new research reveals why. Scientists found that microglia, immune cells in the brain, mistakenly remove nerve fibers connecting the locus coeruleus and olfactory bulb—two regions essential for processing odors.

Featured Neurology Neuroscience

·August 14, 2025·10 min read

Could Restoring Lithium Levels Help Prevent Alzheimer’s Disease?

A decade-long investigation has revealed that natural lithium in the brain helps shield against Alzheimer’s disease by maintaining healthy function across all major brain cell types. Researchers found that lithium loss is one of the earliest brain changes in Alzheimer’s, often occurring before noticeable symptoms.

This shows an older woman and a cat. A brain is in the background.

Featured Neurology Neuroscience

·August 12, 2025·5 min read

Feline Dementia Mirrors Human Alzheimer’s

A new study shows that cats with dementia exhibit brain changes strikingly similar to those seen in Alzheimer’s disease, including the toxic build-up of amyloid-beta in synapses. These changes disrupt connections between brain cells and contribute to memory and thinking decline.

Featured Genetics Neurology Neuroscience

·August 11, 2025·5 min read

Reshaping Nuclear Speckles Could Halt Alzheimer’s

A groundbreaking study reveals that reshaping nuclear speckles — tiny structures inside cell nuclei that regulate protein maintenance — could be a novel way to treat proteinopathies like Alzheimer’s, Parkinson’s, and prion diseases. Researchers found that pyrvinium pamoate, an existing FDA-approved drug, alters the surface tension of nuclear speckles, making them less round and more effective at supporting proteostasis.