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Study explains why a moody gut often accompanies depression

Neuroscience News
Mice with a genetic mutation linked to severe depression had impaired ability for neurons in the gut and brain to create serotonin. The reduction of serotonin in the gut led to a deterioration in the gut's lining, slowing the movement of contents through the GI tract and resulting in constipation. However, treatment with 5-HTP increased neurogenesis in the gut, restoring normal function.... Read More...
FeaturedGeneticsNeurosciencePsychology9 min read
This shows a heatmap of pfc neurons

Possible link between autism and antidepressants use during pregnancy: Mouse Study

Neuroscience News
A new study in mice reveals a possible link between the use of SSRI antidepressants during pregnancy and an increased risk of autism-like symptoms in offspring. Offspring exposed to fluoxetine (Prozac) in utero were more likely to exhibit impaired neurotransmission caused by an overactive serotonin receptor in the prefrontal cortex, an area of the brain implicated in modulating social behaviors. However, treating the mice with a compound that blocks the receptor alleviated the behavioral problems and improved working memory.... Read More...
AutismFeaturedNeuroscienceOpen Neuroscience ArticlesPsychology5 min read