Researchers look at how sensory organs in the skin work, The findings may help solve certain sensory pain disorders.
Serotonin produced by the raphe is critical for sleep in both mice and zebrafish. The firing of neurons in the raphe and the release of serotonin may help the brain build up better sleep pressure. The results may explain why some sleep-related side effects of antidepressants increase serotonin in the brain.
A new study describes the role serotonin plays in brain development.
SERT Ala56 impacts the structure of the SERT protein cells, increasing the activity of the transporter to abnormally high levels. The high-activity state results in the removal of too much serotonin from brain sites where serotonin is needed, both during development and in adults.
Researchers discover elevated levels of TG2 in the prefrontal cortex of people who committed suicide.
Mice with a genetic mutation linked to severe depression had impaired ability for neurons in the gut and brain to create serotonin. The reduction of serotonin in the gut led to a deterioration in the gut's lining, slowing the movement of contents through the GI tract and resulting in constipation. However, treatment with 5-HTP increased neurogenesis in the gut, restoring normal function.
Researchers have created new 3D maps of two melatonin receptors. The models can be used to help develop new treatments that not only improve sleep, but may also treat a variety of other conditions from diabetes to cancer.
Long term stimulation of the serotonin system makes mice more active, a new study reports.