Hands of People With Diabetes More Often Affected by Trigger Finger

Summary: Trigger finger, a condition in which the fingers get locked into a bent position and become difficult to straighten, is more common in those with diabetes than in the general population. High blood sugar levels increase the risk of developing trigger finger, researchers say.

Source: Lund University

Locked fingers, known as trigger finger, are more common among people with diabetes than in the general population. A study led by Lund University in Sweden shows that the risk of being affected increases in the case of high blood sugar. The study has been published in Diabetes Care

Trigger finger means that one or more fingers, often the ring finger or thumb, ends up in a bent position that is difficult to straighten out. It is due to the thickening of tendons, which bend the finger, and their connective tissue sheath, which means that the finger becomes fixed in a bent position towards the palm. It is a painful condition that can often be treated with cortisone injections, but sometimes requires surgery.  

“At the hand surgery clinic, we have noted for a long time that people with diabetes, both type 1 and type 2, are more often affected by trigger finger. Over 20 percent of those who require surgery for this condition are patients who have, or will develop, diabetes,” says Mattias Rydberg, doctoral student at Lund University, resident physician at Skåne University Hospital and first author of the study.

To study whether high blood sugar (blood sugar dysregulation) increases the risk of trigger finger, the researchers examined two registers: Region Skåne’s healthcare database, which includes all diagnoses, and the Swedish national diabetes register. Between 1 and 1.5 percent of the population are affected by trigger finger, but the diagnosis arises among 10-15 percent of those who have diabetes, and the phenomenon appears most in the group with type 1 diabetes. 

The newly published study strengthens the pattern of blood sugar being a crucial factor for an increased risk of being affected by trigger finger. High blood sugar increased the risk of being affected by trigger finger among both men and women in the groups with type 1 diabetes and type 2 diabetes.

Blood sugar is measured in HbA1C, also referred to as long-term blood sugar, and when regulated, is under 48. The group of men with the worst regulated blood sugar (HbA1C > 64) had up to 5 times as high a risk of being affected than men with well-regulated (HbA1< 48) blood sugar. 

“However, we can’t know for certain if any of the groups seek healthcare more often than others which could be a factor that affects the results,” says Mattias Rydberg. 

The mechanism, or mechanisms, behind the increased risk are unknown, but there are theories that high blood sugar makes both the flexor tendons and their connective tissue sheaths thicker, thus causing them to lock more easily. It was previously known that those with unregulated blood sugar are more prone to nerve entrapments in the hand.

“It is important to draw attention to the complications from diabetes and how they can arise in order to discover them early, which enables faster treatment and thus a better outcome.

This shows a person's hand with the index finger pointed
The newly published study strengthens the pattern of blood sugar being a crucial factor for an increased risk of being affected by trigger finger. Image is in the public domain

“In addition to nerve compressions and trigger finger, there may also be a link with thickening of the connective tissue in the palm (Dupuytren’s contracture), impairment of joint movement and the risk of arthritis at the base of the thumb. The mechanisms behind these complications probably differ in the case of diabetes.

“The results of this study are interesting, as we can show that blood sugar dysregulation has a connection with the development of trigger finger,” says Lars B. Dahlin, professor at Lund University and consultant in hand surgery at Skåne University Hospital. 

The next step in the research will be to chart how effective it is to operate on patients with diabetes who are affected by trigger finger. 

“From our experience at the clinic, surgery goes well and there are few complications, but it takes a little longer for patients with type 1 and type 2 diabetes to regain full movement and function. We want to investigate this hypothesis further. Another interesting idea is to see if trigger finger could be a warning signal for type 2 diabetes.

“It is far from all who are affected by trigger finger that have diabetes, but it would be interesting to see if by using modern registers we can discover those who are in the risk zone for developing diabetes,” concludes Mattias Rydberg.

About this diabetes research news

Author: Lotte Billing
Source: Lund University
Contact: Lotte Billing – Lund University
Image: The image is in the public domain

Original Research: Closed access.
High HbA1c Levels Are Associated With Development of Trigger Finger in Type 1 and Type 2 Diabetes: An Observational Register-Based Study From Sweden” by Mattias Rydberg et al. Diabetes Care


High HbA1c Levels Are Associated With Development of Trigger Finger in Type 1 and Type 2 Diabetes: An Observational Register-Based Study From Sweden


Trigger finger (TF) is a hand disorder causing the fingers to painfully lock in flexion. Diabetes is a known risk factor; however, whether strict glycemic control effectively lowers risk of TF is unknown. Our aim was to examine whether high HbA1c was associated with increased risk of TF among individuals with diabetes.


The Swedish National Diabetes Register (NDR) was cross-linked with the health care register of the Region of Skåne in southern Sweden. In total, 9,682 individuals with type 1 diabetes (T1D) and 85,755 individuals with type 2 diabetes (T2D) aged ≥18 years were included from 2004 to 2019. Associations between HbA1c and TF were calculated with sex-stratified, multivariate logistic regression models with 95% CIs, with adjustment for age, duration of diabetes, BMI, and systolic blood pressure.


In total, 486 women and 271 men with T1D and 1,143 women and 1,009 men with T2D were diagnosed with TF. Increased levels of HbA1c were associated with TF among individuals with T1D (women OR 1.26 [95% CI 1.1–1.4], P = 0.001, and men 1.4 [1.2–1.7], P < 0.001) and T2D (women 1.14 [95% CI 1.2–1.2], P < 0.001, and men 1.12 [95% CI 1.0–1.2], P = 0.003).


Hyperglycemia increases the risk of developing TF among individuals with T1D and T2D. Optimal treatment of diabetes seems to be of importance for prevention of diabetic hand complications such as TF.

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  1. I have trigger fingers but I have rheumatoid arthritis. I don’t have diabetes however. Never have

    1. I have had trigger finger in my left third finger was gone get surgery but it heal on its own. Now I have tagger finger in my left thumb and the pain hurts bad I have to wear a splint on my thumb to help with the locking of my thumb. It move from one finger to my thumb.

  2. Type 2, had 1 tfinger, few years later, 2 more. The second 2 came during a period of mass sugar consumption.

  3. My wife recently had an episode of trigger finger that was very painful. The ER doctor showed her how there was a small bump in her palm that was responsible for the event.

  4. My wife recently had an episode of trigger finger that was very painful. The ER doctor showed her how there was a small bump in her palm that was responsible for the event.

  5. I have been a T2 diabetic for about twenty five years now and about one year ago I started developing TF and it was quite painful. I began forcing it straight by pulling with my other hand and it was very painful but I could tell that it helped. I continued doing this for weeks and it is now back to normal as if there never was a problem.

  6. I’ve had surgeries on my left trigger finger, right trigger finger & right long finger. They all have been successful. I have type 2 diabetes. This article has been very informative for me.

  7. No kidding.I had type 1 for 32 years before a transplant. I’ve had 5 trigger fingers in total 2 at one time one on each hand. (Don’t have them fixed at the same time.) Diabetes, the gift that keeps on giving.

  8. Can confirm. Type 1 diabetic since I was 1 and have had two surgeries for trigger finger. One in each hand, and it’s back again in one of them. Assuming a third surgery is in my future. Also have Dupuytren’s , unrelated to the trigger finger.

    1. Thank you, Jennifer, for pointing out the “TYPO” in the article!
      I am glad I read all the comments to see if anyone had caught the mistake! WOW!

      Someone in the Neuroscience News proof reading and publishing department REALLY MADE A TERRIBLE MISTAKE HERE AND THEY NEED TO FIX IT ASAP! How can we get them to notice and CORRECT the article, above?

      Trigger finger is also caused from a B-6 DEFICIENCY! I have treated several patients for this, and it always seemed to be associated with the over consumption of SUGAR and White Flour, high Carbohydrate diets, which turns into sugar! Sugar DEPLETES a person’s B Vitamin balance! B vitamins are crucial for nerve function!
      Thanks to this article, now I have more evidence! Thank you, Neuroscience News!

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