New research could contribute to designing new treatment options for spinal cord injuries.
A new procedure could restore function to muscles involved in breathing control for paralyzed patients.
Researchers develop a highly flexible neural probe, created from polymers, which can both record and optically stimulate neural activity in the spinal cord of mice.
Researchers identify two types of neurons which enable the spinal cord to control skilled forelimb movement.
Researchers have identified a polio-like syndrome in a group of five California based children over a one year period.
Researchers reprogram astrocytes to become functional neurons in living mammals.
Researchers find differential control of an animal's musculature is already in place in the spinal networks of simple fish.
Researchers have developed a new, non invasive, imaging tool that can visualize myelin damage in patients with MS.
Researchers identify neuronal circuits in the spinal cord of mice which control the ability to produce alternating movements of the legs during walking.
A training regimen to adjust the body's motor reflexes may help improve mobility for some people with incomplete spinal cord injuries. During training, the participants were instructed to suppress a knee jerk-like reflex elicited by a small shock to the leg. Those able to calm hyperactive reflexes saw improvements in their walking.
Doctors performed the first-ever FDA approved Schwann cell transplantation in a patient with a new spinal cord injury. The procedure is a Phase 1 clinical trial designed to evaluate the safety and feasibility of transplanting the patient’s own Schwann cells.
A new finding turns one of the basics of neurobiology on its head, demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.
A study suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought. In a second study, the researchers identified the molecular pathway in SMA that leads to problems with motor function.
Researchers were able to regenerate an astonishing degree of axonal growth at the site of severe spinal cord injury in rats. Results were then replicated using two human stem cell lines, one already in human trials for ALS. “We obtained the exact results using human cells as we had in the rat cells,” said Tuszynski.
Scientists knew that mutations in the FUS gene (Fused in Sarcoma) cause amyotrophic lateral sclerosis (ALS), a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement. The researchers were successful in identifying mutations in this gene that cause Essential Tremor, and proved that the disease mechanisms for ET and ALS FUS mutations are different.