A training regimen to adjust the body’s motor reflexes may help improve mobility for some people with incomplete spinal cord injuries. During training, the participants were instructed to suppress a knee jerk-like reflex elicited by a small shock to the leg. Those able to calm hyperactive reflexes saw improvements in their walking.
Doctors performed the first-ever FDA approved Schwann cell transplantation in a patient with a new spinal cord injury. The procedure is a Phase 1 clinical trial designed to evaluate the safety and feasibility of transplanting the patient’s own Schwann cells.
A new finding turns one of the basics of neurobiology on its head, demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.
A study suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought. In a second study, the researchers identified the molecular pathway in SMA that leads to problems with motor function.
Researchers were able to regenerate an astonishing degree of axonal growth at the site of severe spinal cord injury in rats. Results were then replicated using two human stem cell lines, one already in human trials for ALS. “We obtained the exact results using human cells as we had in the rat cells,” said Tuszynski.
Scientists knew that mutations in the FUS gene (Fused in Sarcoma) cause amyotrophic lateral sclerosis (ALS), a disease of the nerve cells in the brain and spinal cord that control voluntary muscle movement. The researchers were successful in identifying mutations in this gene that cause Essential Tremor, and proved that the disease mechanisms for ET and ALS FUS mutations are different.
Georgia Tech researchers have created a wireless, musical glove that may improve sensation and motor skills for people with paralyzing spinal cord injury (SCI).
Researchers from the Bellvitge Biomedical Research Institute at the University of Barcelona have coordinated research into how the IDPN nitrile causes neurological syndromes similar to those of the amyotrophic lateral sclerosis (ALS), a severe neuromuscular degenerative disease.
Mice born with Spinal Muscular Atrophy typically only live five to six days. University of Missouri researchers introduced the SMN gene into the mice’s central nervous systems and were able to extend their lives 10-25 days longer.
Millions of people suffering from multiple sclerosis, Parkinson’s, muscular dystrophy, spinal cord injuries or amputees could soon interact with their computers and surroundings using just their eyes, thanks to a new device that costs less than £40 (~$63).