Inhibitory neurons in the spinal cord lose their connections to motor neurons in mouse models of ALS. While no connection between this deterioration to the development of ALS has been made, researchers say the loss of inhibitory signals could explain why motor neurons die in those with ALS.
Researchers have identified acute transverse myelitis (ATM) in a number of COVID-19 patients. ATM, which is marked by inflammation of the spinal cord, is a rare neurological disorder that can lead to spinal cord lesions, paralysis, and bowel dysfunction.
People with spinal cord injuries have the same brain activity during processing speed tasks as healthy older adults. The findings suggest the theory of accelerated cognitive aging following SCI is correct.
Researchers combined intact neurons from a rat's spinal cord with a tissue-engineered 3D muscle system, creating a biohybrid robot, or biobot. After culturing the system for seven days, the motor neurons from the spinal cord produced electrical activity, causing contractions in the artificial muscles and mimicking the behavior of the peripheral nervous system. The findings could have positive implications for the treatment of neurodegenerative disorders that affect motor control.
Using robotics, researchers uncover mechanisms in the cerebellum and spinal cord that determine how the nervous system responds to induced changes in step length. The findings could have implications for physical rehabilitation programs for people with movement disorders.
A new study challenges existing theories about spinal cord neurons. New findings suggest neurological signals originate from a major, scattered network of cells that send signals to only a few other neurons.