The image shows pencil drawings of sea lampreys by Alexander Francis Lydon.

Scientists Find Genes Linked to Human Neurological Disorders in Sea Lamprey Genome

Scientists have identified several genes linked to human neurological disorders, such as Alzheimer’s disease, Parkinson’s disease and spinal cord injury, in the sea lamprey. The lamprey has large, identified neurons in its brain and spinal cord, making it an excellent model to study regeneration at the single cell-level.
The image shows lead researcher Paolo Macciarini performing surgery.

Stem Cell Based Bioartificial Tissues and Organs

Known for successfully transplanting a bioengineered stem cell-based trachea, surgeon Paolo Macchiarini plans to use his technique to recreate more complex tissue. He has recently made attempts to regenerate brain tissue in rats and mice.
The image shows a coronal MRI scan of a patient with ALS.

Novel Protein May Help Detect Lou Gehrig’s Disease and Dementia

Researchers discover an abnormal protein that accumulates in the brains of patients affected with ALS and frontotemporal dementia. The findings have uncovered a potentially new therapeutic target and biomarker that would allow clinicians to confirm diagnosis of the diseases.
The image shows a capillary regeneration model. The caption best describes the image.

Simulations Show how Blood Vessels Regroup after Stroke

By simulating patterns of microvasculature cell growth and compare the results with real networks grown in lab, researchers hope to direct how they grow into the tiny blood vessels that feed the brain and help people regain functions lost to stroke and disease.
The image shows an over-sized terminal forms a synapse with a dendritic spine. The caption best describes the image.

Excess Protein Linked to Development of Parkinson’s Disease

Researchers suggest the overexpression of a protein called alpha-synuclein appears to disrupt vital recycling processes in neurons. The study may have major implications for more fully understanding the causes and mechanisms of Parkinson’s disease.