Six potential drug candidates have been identified as candidates to treat COVID-19 infections. The drugs, which have previously been subjected to clinical trials for treating a range of conditions, from arthritis to cancer, target Mpro, the main SARS-CoV-2 enzyme.
The first MRI-based mapping of the squid brain yields 145 new connections and pathways, 60% of which are linked to the motor and visual systems. The new brain map brings researchers one step closer to understanding how the squid can instantly camouflage itself.
A new study into human and plant cell apoptosis could provide new avenues for the development of treatments for neurodegenerative diseases, and help develop disease-resistant plants.
A microscopy study revealed tau controls Fyn clustering in dendrites. The findings shed new light on how certain forms of dementia may occur.
Nineteen gene sets have been identified that contribute to at least five psychiatric disorders. The gene sets were associated with ADHD, ASD, bipolar disorder, major depressive disorder, and schizophrenia.
NAPRT1, a gene that encodes an enzyme involved in vitamin B3 metabolism, may be a risk factor for schizophrenia. Knocking out the gene in zebrafish models, researchers discovered brain development became impaired. Without NAPRT1, the fish brains failed to divide symmetrically, which is significant as defects in the corpus callosum have been identified in those with schizophrenia.
Women who experience depression have an increased risk of developing multiple chronic diseases, such as diabetes and hypertension.
Researchers report vitamin D levels affect perineuronal nets in the hippocampus. The study found vitamin D deficiency resulted in a significant decline in memory and learning in mouse models.