New deep learning model can accurately identify sleep stages
A new deep learning algorithm can distinguish different sleep stages. The technology could help with diagnosing sleep disorders, such as obstructive sleep apnea.... Read More...
University of Eastern Finland
Antipsychotics associated with increased risk of head & brain injuries in persons with Alzheimer’s disease
Alzheimer's patients who used antipsychotics had a 29% increased risk of head injury and a 22% higher risk of TBI compared to others with the neurodegenerative disease who did not use the medications.... Read More...
Frontotemporal dementia is associated with alterations in immune system function
Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer.... Read More...
Alzheimer’s disease risk gene APOE4 impairs function of brain immune cells
APOE4 increases the inflammatory response of human microglia while reducing cellular migration. The gene also impairs the metabolic activity of the immune cells. The findings show APOE4 has a profound impact on the basic functions of microglia.... Read More...
The neurobiological mechanisms behind schizophrenia may depend on gender
Schizophrenia is linked to alterations in pathways associated with glycosaminoglycan, neurotransmitter metabolism, and GABAergic synapses. A large percentage of genes related to schizophrenia are expressed differently between males and females. The results imply the mechanisms involved in schizophrenia development differ, at least slightly, between males and females.... Read More...
Abnormal expression of genes in psychopathy
Psychopathy is associated with altered expression of genes and immune responses related to molecular pathways. In neurons, the up-regulation of PRL10P9 and ZNF132 and down-regulation of CDG5 and OPRD1 were linked to psychopathic behaviors. The genetic expression explained up to 92% of the variance of psychopathic symptoms. Researchers speculated these genes may be relevant to the lack of empathy and emotional callousness associated with psychopathy, as previous studies have linked a number of these genes to ASD and problematic social behaviors.... Read More...
Dietary choline associated with reduced risk of dementia
Adding extra choline through eggs or meat to your daily diet could help stave off the effects of dementia. Higher phosphatidylcholine intake through diet was associated with lower rates of dementia and improved cognitive function in aging men.... Read More...
Newly discovered gene mutation reduces fear and anxiety, and increases social interaction
The Ph4-tm gene has been implicated in fear and anxiety. P4h-tm knockout mice showed diminished response to fear and showed more courageous behavior than wild-type mice with a functional P4h-tm gene.... Read More...
Boys with Good Motor Skills Excel at Problem Solving Too
Researchers report boys with better motor skills tend to have higher cognitive scores over a two year follow up period than those with poorer motor skills. Additionally, boys with higher aerobic fitness had poorer cognition during the two year follow up than those with lower fitness levels.... Read More...
Gestational Diabetes May Predispose Women to Postnatal Depression
A new study reveals 16% of new mothers who suffered gestational diabetes while pregnant developed postnatal depression symptoms following birth. Only 9% of women who didn't suffer GDM went on to develop PND. Researchers say gestational diabetes could be used as a biomarker for assessing PND risk following birth.... Read More...
Drinking Changes Young Adults’ Metabolite Profile
Researchers report metabolite profiles alter in young people who consume alcohol at socially acceptable levels. Additionally, researchers found reduced gray matter volume in young women who are heavy drinkers.... Read More...
Sensory Based Food Education Encourages Children to Eat Fruit and Veg
Researchers report sensory based food education encourages healthier eating choices in kindergarten aged children.... Read More...