University of Eastern Finland

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University of Eastern Finland

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 16, 2019·4 min read

Frontotemporal dementia is associated with alterations in immune system function

Researchers discovered increased inflammatory activity in a subgroup of patients with frontotemporal dementia. The increased inflammation was indicated by elevated levels of cytokines known to increase inflammatory response and decreased levels of IL-10, which reduces inflammation. The inflammation was associated with Parkinsonism's symptoms and rapid cognitive and functional decline. The study also revealed patients with FTD are less likely to develop cancer.

Featured Genetics Psychology

·February 21, 2018·3 min read

Depression Linked to Reduced Arginine Levels

Researchers have identified a link between reduced arginine levels and major depressive disorder.

Featured Neurology Neuroscience

·January 16, 2020·3 min read

Antipsychotics associated with increased risk of head & brain injuries in persons with Alzheimer’s disease

Alzheimer's patients who used antipsychotics had a 29% increased risk of head injury and a 22% higher risk of TBI compared to others with the neurodegenerative disease who did not use the medications.

Featured Neurology Psychology

·April 4, 2017·2 min read

Psychiatric Disorder Do Not Increase Alzheimer’s Risk

According to researchers, there is no link between psychiatric disorders and an increased risk of developing Alzheimer's disease.

Featured Neuroscience

·July 1, 2018·3 min read

Drinking Changes Young Adults’ Metabolite Profile

Researchers report metabolite profiles alter in young people who consume alcohol at socially acceptable levels. Additionally, researchers found reduced gray matter volume in young women who are heavy drinkers.

This shows a male and female head surrounded by different colors

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·September 3, 2019·3 min read

The neurobiological mechanisms behind schizophrenia may depend on gender

Schizophrenia is linked to alterations in pathways associated with glycosaminoglycan, neurotransmitter metabolism, and GABAergic synapses. A large percentage of genes related to schizophrenia are expressed differently between males and females. The results imply the mechanisms involved in schizophrenia development differ, at least slightly, between males and females.

Featured Neurology Neuroscience

·August 20, 2021·3 min read

Physical Exercise Modulates Iron in Alzheimer’s Disease

Regular exercise modulates iron storage and trafficking in the brain and skeletal muscles, and physical activity reduces cortical hepcidin. The findings reveal how exercise can be beneficial for those with Alzheimer's disease.

Featured Neuroscience

·December 17, 2018·4 min read

Boys with Good Motor Skills Excel at Problem Solving Too

Researchers report boys with better motor skills tend to have higher cognitive scores over a two year follow up period than those with poorer motor skills. Additionally, boys with higher aerobic fitness had poorer cognition during the two year follow up than those with lower fitness levels.

Featured Genetics Neuroscience Open Neuroscience Articles

·September 25, 2020·5 min read

A Genetic Variant That Protects Against Alzheimer’s Promotes Immune Cell Functions

PLCG2-P522R, a genetic variant that protects against Alzheimer's disease, enhances key functions of immune cells.

Image shows a woman holding her head in pain.

Featured Neurology Pain

·January 4, 2017·3 min read

Vitamin D Deficiency Increases Chronic Headache Risk

A new study links frequent chronic headaches with lower serum vitamin D levels.

Featured Genetics Neuroscience

·May 2, 2019·4 min read

Newly discovered gene mutation reduces fear and anxiety, and increases social interaction

The Ph4-tm gene has been implicated in fear and anxiety. P4h-tm knockout mice showed diminished response to fear and showed more courageous behavior than wild-type mice with a functional P4h-tm gene.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 16, 2019·4 min read

Alzheimer’s disease risk gene APOE4 impairs function of brain immune cells

APOE4 increases the inflammatory response of human microglia while reducing cellular migration. The gene also impairs the metabolic activity of the immune cells. The findings show APOE4 has a profound impact on the basic functions of microglia.

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