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TMEM106B

This shows the structure of the proteins

Featured Genetics Neurology Neuroscience

·April 23, 2022·5 min read

Unexpected Protein Could Play Role Frontotemporal Dementia

Amyloid fibrils in those with frontotemporal lobar degeneration (FTLD) contain a little-known protein called TMEM106B. Researchers speculate TMEM106B could be found to be the cause of FTLD.

Featured Genetics Neurology

·August 19, 2020·4 min read

Potential Link for Alzheimer’s Disease and Common Brain Disease That Mimics Its Symptoms

Researchers identified a group of closely related genes that capture molecular links between Alzheimer's and LATE, a common brain disorder that mimics Alzheimer's symptoms.

This shows someone holding an old person's hands

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 30, 2019·5 min read

When is Alzheimer’s not Alzheimer’s? Researchers characterize a different form of dementia

LATE, a form of dementia that appears in the oldest-old is often mistaken for Alzheimer's disease, but the brain pathology is very different. The protein TDP-43 appears to play a significant role in the development of LATE. The neurodegenerative disease may progress more gradually than Alzheimer's, but when combined with Alzheimer's disease (a common combination), appears to cause a more rapid decline than either would alone.