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          synaptic plasticity

          This shows a person and swirly lines.
          FeaturedNeuroscience
          ·April 23, 2025·4 min read

          Psychedelic Sparks Long-Term Brain Plasticity

          A single dose of the psychedelic compound 25CN-NBOH significantly improved cognitive flexibility in mice, with effects lasting up to three weeks post-treatment. Treated mice adapted more quickly in rule-switching tasks, indicating enhanced neuroplasticity in the prefrontal cortex.
          Read More
          This shows synapses.
          FeaturedNeuroscience
          ·April 17, 2025·5 min read

          Synapses Use Multiple Learning Rules to Encode New Information

          New research reveals that individual neurons follow multiple learning rules simultaneously, challenging the long-held belief that synaptic plasticity operates uniformly throughout the brain. Using advanced two-photon imaging, scientists tracked changes in synapses during learning in mice, uncovering that different regions within a single neuron adapt using distinct plasticity mechanisms.
          Read More
          This shows a brain.
          AutismFeaturedNeuroscience
          ·April 7, 2025·5 min read

          Thalamus Identified As a Hub for Memory and Brain Plasticity

          A new study reveals that the thalamus, long overshadowed by the cortex and hippocampus, plays a crucial role in shaping and updating brain connections. Researchers observed plasticity in thalamic neurons in response to visual experiences, independent of the cortex—an unexpected finding.
          Read More
          This shows a brain.
          FeaturedNeuroscience
          ·April 1, 2025·5 min read

          Brain Mapping Tool Reveals How Learning Rewires Synaptic Links

          Researchers have developed DELTA, a powerful new imaging method that maps brain-wide synaptic changes during learning. By labeling synaptic proteins before and after behavioral training, scientists can now visualize where and how neural connections shift over time.
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          This shows a brain.
          FeaturedNeuroscience
          ·March 20, 2025·7 min read

          Brain’s Memory Maps Constantly Evolve to Capture Changing Experiences

          A new study reveals that memory-related brain activity continues to shift even after learning, challenging traditional views of stable neural representations. Researchers analyzed hippocampal neurons in mice and found that their "place cells," which encode spatial memory, subtly changed each time the mice revisited a familiar environment.
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          This shows a statue of a neuron.
          FeaturedGeneticsNeuroscience
          ·October 24, 2024·6 min read

          Yamanaka Factors Can Reverse Neuronal Aging

          Yamanaka factors can reverse aging in brain neurons, improving synaptic connections, metabolism, and protecting against neurodegenerative diseases like Alzheimer's. Researchers introduced the Yamanaka factors into neurons of adult mice, finding that this process rejuvenated the cells without negative side effects, even enhancing motor and social behaviors.
          Read More
          This shows two heads.
          FeaturedNeuroscience
          ·October 10, 2024·3 min read

          Bilingual Brains Build Stronger Connections

          New research demonstrates that learning a second language enhances brain connectivity, particularly when started in childhood. Scientists found that bilingual individuals have more efficient communication between brain regions, notably between the cerebellum and left frontal cortex.
          Read More
          This shows a neuron.
          FeaturedNeuroscience
          ·October 9, 2024·6 min read

          How Brains Learn Over Longer Timescales

          Researchers have discovered a novel brain mechanism, behavioral timescale synaptic plasticity (BTSP), that enables neurons to encode information over seconds rather than milliseconds, aligning more closely with learning timescales. Previously, encoding models like Hebbian plasticity focused on neuron activity within mere milliseconds, but BTSP extends this window, allowing neurons to integrate information over seconds.
          Read More
          This shows a brain.
          FeaturedGeneticsNeuroscience
          ·September 27, 2024·3 min read

          Enzyme Key to Brain Function and Synapse Health Discovered

          A new study reveals that the absence of the TRMT10A enzyme disrupts tRNA levels, leading to impaired protein synthesis and brain function. Researchers found that mice lacking the Trmt10a gene had decreased levels of key tRNAs, which affected neuronal synapses and cognitive abilities.
          Read More
          This shows the outline of a woman and a brain.
          FeaturedNeuroscience
          ·September 21, 2024·5 min read

          Pregnancy Dramatically Reshapes the Brain

          A new study provides the first detailed map of brain changes during pregnancy, showing significant neuroplasticity in adults. Researchers found a decrease in gray matter volume and a temporary increase in white matter in a pregnant brain.
          Read More
          This shows a head and neurons.
          FeaturedGeneticsNeurosciencePsychology
          ·September 5, 2024·6 min read

          Schizophrenia Linked to Disrupted Synaptic Plasticity

          Researchers have identified a mechanism that impairs synaptic plasticity in individuals with schizophrenia, revealing the role of three key proteins. Using computational modeling, the team explored how genetic alterations affect the brain’s ability to strengthen or weaken synaptic connections, a crucial process for memory and learning.
          Read More
          This shows neurons.
          FeaturedNeuroscience
          ·August 8, 2024·5 min read

          Synaptic Quality Key to Age Related Memory Preservation

          A recent study reveals that the quality, not the quantity, of synapses in the brain is crucial for preserving memory in older adults. Researchers found that larger dendritic spine head diameters in the temporal cortex correlate with better episodic memory performance, challenging the long-held belief that memory decline is primarily due to synapse loss.
          Read More
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          This shows two heads, one made of DNA and the other of environmental factors.

          100,000 Small Factors Rival DNA in Disease Risk

          This shows a person in a dark room and golden sound waves.

          The Brain Stacks Sound Information to Navigate the Dark

          This shows a pigeon pecking at colored lines.

          Edge of Chaos: Why Pigeons Refuse to Become “Machines”

          This shows a head and a question mark.

          Brain’s Default Setting for Ambiguity Matters for Mental Health

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