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          synaptic plasticity

          This shows a brain.
          FeaturedNeuroscience
          ·May 9, 2025·6 min read

          How Memories Take Shape at the Synapse Level

          A groundbreaking new technique called EPSILON allows researchers to map the proteins involved in memory formation with unprecedented detail, providing a window into the molecular architecture of learning. This approach focuses on tracking AMPARs—key receptors that regulate synaptic strength—over time, illuminating how the brain encodes, strengthens, and stores memories.
          Read More
          This shows a person sitting and mushrooms.
          FeaturedNeurologyNeuroscience
          ·April 30, 2025·6 min read

          Psilocybin Shows Promise for Parkinson’s Mood and Motor Symptoms

          A new pilot study reveals that psilocybin—the compound found in psychedelic mushrooms—may significantly improve mood, cognition, and motor function in people with Parkinson’s disease. The compound was well tolerated, with only mild side effects, and benefits persisted for weeks after dosing. While the study was primarily designed to test safety, researchers observed meaningful and lasting improvements in multiple symptoms.
          Read More
          This shows a person and swirly lines.
          FeaturedNeuroscience
          ·April 23, 2025·4 min read

          Psychedelic Sparks Long-Term Brain Plasticity

          A single dose of the psychedelic compound 25CN-NBOH significantly improved cognitive flexibility in mice, with effects lasting up to three weeks post-treatment. Treated mice adapted more quickly in rule-switching tasks, indicating enhanced neuroplasticity in the prefrontal cortex.
          Read More
          This shows synapses.
          FeaturedNeuroscience
          ·April 17, 2025·5 min read

          Synapses Use Multiple Learning Rules to Encode New Information

          New research reveals that individual neurons follow multiple learning rules simultaneously, challenging the long-held belief that synaptic plasticity operates uniformly throughout the brain. Using advanced two-photon imaging, scientists tracked changes in synapses during learning in mice, uncovering that different regions within a single neuron adapt using distinct plasticity mechanisms.
          Read More
          This shows a brain.
          AutismFeaturedNeuroscience
          ·April 7, 2025·5 min read

          Thalamus Identified As a Hub for Memory and Brain Plasticity

          A new study reveals that the thalamus, long overshadowed by the cortex and hippocampus, plays a crucial role in shaping and updating brain connections. Researchers observed plasticity in thalamic neurons in response to visual experiences, independent of the cortex—an unexpected finding.
          Read More
          This shows a brain.
          FeaturedNeuroscience
          ·April 1, 2025·5 min read

          Brain Mapping Tool Reveals How Learning Rewires Synaptic Links

          Researchers have developed DELTA, a powerful new imaging method that maps brain-wide synaptic changes during learning. By labeling synaptic proteins before and after behavioral training, scientists can now visualize where and how neural connections shift over time.
          Read More
          This shows a brain.
          FeaturedNeuroscience
          ·March 20, 2025·7 min read

          Brain’s Memory Maps Constantly Evolve to Capture Changing Experiences

          A new study reveals that memory-related brain activity continues to shift even after learning, challenging traditional views of stable neural representations. Researchers analyzed hippocampal neurons in mice and found that their "place cells," which encode spatial memory, subtly changed each time the mice revisited a familiar environment.
          Read More
          This shows a statue of a neuron.
          FeaturedGeneticsNeuroscience
          ·October 24, 2024·6 min read

          Yamanaka Factors Can Reverse Neuronal Aging

          Yamanaka factors can reverse aging in brain neurons, improving synaptic connections, metabolism, and protecting against neurodegenerative diseases like Alzheimer's. Researchers introduced the Yamanaka factors into neurons of adult mice, finding that this process rejuvenated the cells without negative side effects, even enhancing motor and social behaviors.
          Read More
          This shows two heads.
          FeaturedNeuroscience
          ·October 10, 2024·3 min read

          Bilingual Brains Build Stronger Connections

          New research demonstrates that learning a second language enhances brain connectivity, particularly when started in childhood. Scientists found that bilingual individuals have more efficient communication between brain regions, notably between the cerebellum and left frontal cortex.
          Read More
          This shows a neuron.
          FeaturedNeuroscience
          ·October 9, 2024·6 min read

          How Brains Learn Over Longer Timescales

          Researchers have discovered a novel brain mechanism, behavioral timescale synaptic plasticity (BTSP), that enables neurons to encode information over seconds rather than milliseconds, aligning more closely with learning timescales. Previously, encoding models like Hebbian plasticity focused on neuron activity within mere milliseconds, but BTSP extends this window, allowing neurons to integrate information over seconds.
          Read More
          This shows a brain.
          FeaturedGeneticsNeuroscience
          ·September 27, 2024·3 min read

          Enzyme Key to Brain Function and Synapse Health Discovered

          A new study reveals that the absence of the TRMT10A enzyme disrupts tRNA levels, leading to impaired protein synthesis and brain function. Researchers found that mice lacking the Trmt10a gene had decreased levels of key tRNAs, which affected neuronal synapses and cognitive abilities.
          Read More
          This shows the outline of a woman and a brain.
          FeaturedNeuroscience
          ·September 21, 2024·5 min read

          Pregnancy Dramatically Reshapes the Brain

          A new study provides the first detailed map of brain changes during pregnancy, showing significant neuroplasticity in adults. Researchers found a decrease in gray matter volume and a temporary increase in white matter in a pregnant brain.
          Read More
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          This shows the outline of two people and brains.

          Reducing Visceral Fat Protects the Brain for Decades

          This shows an ancient anthropoid with a brain.

          Brain-First Hypothesis: Rethinking the Cambrian Explosion

          This shows a brain and bar bells.

          Beyond the Gym: Why Your Brain Craves Creatine

          This shows the outline of a head.

          Brain Switch for Action and Stress Identified

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