M1 muscarinic acetylcholine receptor (mAChR) dependent LTP and LTD share a common AMPA trafficking pathway. Either the upregulation of neurotransmitter receptor genes or suppression of the downregulation could improve synaptic dysfunction associated with age-related neurodegeneration. The findings could assist in the creation of new therapies for Alzheimer's disease that target synaptic plasticity.
Sleep deprivation doesn't just alter brain activity, it also changes the connection between neurons. Both changes have a significant effect on working memory and cognitive performance.
Thalamic inputs into superficial layers of the cerebral cortex are both rare and weak, yet surprisingly diverse in their distribution patterns. However, they are reliable and efficient representatives of information.
Artificial neural networks based on human brain dynamics can outperform current deep learning models in learning capabilities.
Findings support modern thought that neural networks store information by making short-term alterations to the synapses. The study sheds new light on short-term synaptic plasticity in recent memory storage.
In the olfactory bulb, levels of oxytocin rise and peak when new neurons incorporate themselves into neural networks. The findings shed new light on adult neurogenesis and brain plasticity.
Researchers find significant changes in fathers' brains between the prenatal and the postpartum period. The main changes occurred in cortical areas associated with visual processing, attention, and empathy toward their baby.
Oligodendrocyte precursor cells (OPCs) play a significant role in synaptic pruning, a new study reveals.
Researchers have identified a new type of synaptic plasticity they call behavioral timescale synaptic plasticity (BTSP). The study reveals how the entorhinal cortex sends instructive signals to the hippocampus and directs it to specifically reorganize the specific location and activity of a neural subset to achieve altered behavior in response to changes in environment and spatial cues.
A new study reveals how our brain swiftly adapts to compensate for dynamic and abrupt essential changes in behavior.
Researchers discuss how psychedelics can affect the brain and provide therapeutic benefits for those suffering from a range of psychiatric disorders.
A new study of the hippocampus reveals immature, plastic neurons are present in significant numbers during the entire lifespan. The findings shed new light on neuroplasticity.