Hypermutation in children may be linked to increased mutations in the sperm of the biological father, especially fathers who received certain forms of chemotherapy to treat cancer early in life.
A genetic disorder caused by protein synthesis that results in learning and developmental difficulties can be treated by spermidine, a compound isolated from human sperm.
Cannabis use in males appears to alter sperm before mating, increasing the risk of their offspring developing brain abnormalities in areas associated with mood, memory, learning, and reward.
Spontaneous mutations in a father's sperm may be linked to autism spectrum disorder in their offspring. UCSD researchers have developed a new method of quantifying the mutations and assessing the likelihood that the mutations will contribute to ASD.
THC exposure targets genes in two major cellular pathways and alters DNA methylation, a new study reports. Researchers say that wile cannabis triggers structural and regulatory changes in the DNA of users' sperm, they do not know yet whether the changes are passed down to the offspring and what effects that could have.
Researchers report a father's exposure to nicotine may have lasting effects on the cognitive development of his offspring. The study reports nicotine exposure may cause epigenetic alterations in key genes within the father's sperm, affecting not only his direct children but also grandchildren.
Researchers report epigenetic modifications in the DNA of sperm in men who had higher phthalate levels.
A new mathematical formula based on the rhythmic movement of a sperm could provide new insights into male infertility.