A new bio-inspired slow-release system for site 1 sodium channel blockers helps release anesthesia, providing prolonged nerve blocking with minimal toxicity.
Researchers establish SCN3A genetic mutations cause infantile epileptic encephalopathy.
Researchers discover changes in the activity of sodium and potassium channels during the day and night impact the sleep-wake cycle.
The findings in a new study could help treat channel related neurological disorders.
Mutations in beta4 proteins could have a surprisingly large effect on health, researchers claim.
The toxic sting from scorpions acts as an analgesic, rather than pain stimulant, in grasshopper mice, new research finds.
Researchers discover sodium channels also play critical roles in non-excitable cells.
Scientists have observed the neurological mechanism behind temperature-dependent febrile seizures by genetically engineering fruit flies to harbor a mutation analogous to one that causes epileptic seizures in people. Their new study also highlights the first use of genetic engineering to swap a human genetic disease mutation into a directly analogous gene in a fly.
A low dose of the sedative clonazepam alleviated autistic-like behavior in mice with a mutation that causes Dravet syndrome in humans.
The achievement opens new possibilities for designing drugs for pain, epilepsy and heart rhythm disturbances Scientists at the University of...