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SCI

·May 22, 2025·6 min read

Implanted Device Restores Arm Function After Spinal Cord Injury

A groundbreaking clinical study shows that closed-loop vagus nerve stimulation (CLV), paired with rehabilitation, can significantly improve arm and hand function in people with chronic spinal cord injuries. The therapy uses a tiny implanted device that sends timed electrical pulses to the brain when patients perform successful movements, helping rewire neural circuits.

This illustration shows a head and glowing lights down the spine.

Featured Neurology Neuroscience

·April 28, 2025·5 min read

Noninvasive Brain-Spine Interface May Help Restore Movement After Injury

Researchers have developed a noninvasive brain-spine interface that detects movement intentions and cues spinal cord stimulation to aid rehabilitation. Using EEG caps, they trained a decoder to recognize when volunteers either moved or imagined moving their legs.

Featured Neurology Neuroscience

·January 7, 2025·4 min read

Unlocking Spinal Cord Regeneration: Astrocytes Lead the Way

Spinal cord injuries (SCI) are challenging to treat due to the limited regenerative capacity of the central nervous system. A new study reveals that while ependymal cells in the spinal cord show minimal repair potential, astrocytes can transdifferentiate into oligodendrocytes, aiding in remyelination.

Featured Genetics Neurology Neuroscience

·December 17, 2024·3 min read

Neural Stem Cell Transplants Show Promise for Spinal Injuries

A Phase I clinical trial has demonstrated the long-term safety of neural stem cell transplantation for chronic spinal cord injuries. Researchers followed four patients for five years, with two showing sustained neurological improvements, including better motor function and sensory responses.

Featured Neurology Neuroscience

·December 2, 2024·6 min read

Brain Stimulation Aids Walking Recovery After Spinal Cord Injury

Researchers have identified the lateral hypothalamus (LH) as a key brain region for walking recovery in spinal cord injury (SCI) patients, demonstrating that deep brain stimulation (DBS) can significantly enhance mobility and autonomy. Unlike traditional DBS applications, targeting the LH promotes long-term neurological improvements, even when stimulation is off. A clinical trial showed dramatic outcomes in participants, with restored walking ability and improved daily independence.

Featured Genetics Neurology Neuroscience

·October 22, 2024·5 min read

Gene Discovery Boosts CNS Regeneration for Spinal Injury Repair

A recent study highlights a novel gene, lipin1, that regulates axon regeneration in the central nervous system, offering new hope for treating spinal cord injuries. The research shows that inhibiting lipin1 enhances lipid metabolism in neurons, activating crucial pathways like mTOR and STAT3 that promote nerve regeneration.

Featured Neurology Neuroscience

·October 17, 2024·4 min read

Microglia Found to Protect Neurons Post-Spinal Cord Injury

Researchers discovered a neuroprotective mechanism in spinal cord injury (SCI) involving microglia, the brain’s immune cells, which could provide new therapeutic targets. Using advanced in vivo imaging, the team revealed that microglia form protective wraps around injured axons, preventing further damage. This interaction, regulated by P2Y12 receptors and sodium channels, sheds light on neuron-glia communication after injury. The study's insights into spinal cord protection could eventually lead to new treatments for SCI and related neurological diseases.

Featured Neurology Neuroscience

·August 27, 2024·5 min read

Miniaturized Brain-Machine Interface Translates Thoughts Into Text

Researchers developed a compact, low-power brain-machine interface (BMI) called MiBMI, designed to enhance communication for individuals with severe motor impairments. The device translates neural activity into text with 91% accuracy, using a highly miniaturized system that processes data in real-time. This innovation opens the door to practical, implantable BMIs, promising significant improvements in quality of life for patients with conditions like ALS and spinal cord injuries.

Featured Neurology Neuroscience

·June 12, 2024·4 min read

New Target for Spinal Cord Injury Treatment Identified

Researchers discovered a druggable target that could prevent autonomic dysfunction after spinal cord injury. The research found that microglia cells control abnormal nerve growth and autonomic reflexes. By depleting microglia in a mouse model, researchers prevented life-threatening complications. This finding could lead to new therapies for spinal cord injuries and other neurological conditions.

Featured Neurology Neuroscience

·May 11, 2024·6 min read

Wrap Around Spinal Cord Device May Transform Injury Treatment

Researchers developed a groundbreaking electronic device that wraps around the spinal cord, offering a new method for treating spinal injuries without the need for brain surgery. This device can record and stimulate nerve signals across the entire spinal cord, providing a complete 360-degree view of spinal activity.

Featured Neurology Neuroscience

·April 24, 2024·7 min read

Spinal Injuries Trigger Metabolic Disorders

A new study demonstrates how spinal cord injuries can lead to significant metabolic disruptions, including the onset of conditions such as diabetes and heart disease. The study found that abnormal neuronal activities post-injury lead to excessive breakdown of triglycerides in fat tissue, releasing harmful compounds into organs like the liver.

Featured Genetics Neurology Neuroscience

·April 2, 2024·7 min read

Stem Cells Spark Hope in Spinal Cord Recovery

A phase 1 clinical trial has revealed that stem cells derived from patients' own fat may safely enhance sensation and movement in individuals with traumatic spinal cord injuries. In the study, seven out of ten adults showed measurable improvements on the ASIA Impairment Scale, experiencing increased sensation, muscle strength, and improved bowel function without serious side effects.

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SCI

Implanted Device Restores Arm Function After Spinal Cord Injury

Noninvasive Brain-Spine Interface May Help Restore Movement After Injury

Unlocking Spinal Cord Regeneration: Astrocytes Lead the Way

Neural Stem Cell Transplants Show Promise for Spinal Injuries

Brain Stimulation Aids Walking Recovery After Spinal Cord Injury

Gene Discovery Boosts CNS Regeneration for Spinal Injury Repair

Microglia Found to Protect Neurons Post-Spinal Cord Injury

Miniaturized Brain-Machine Interface Translates Thoughts Into Text

New Target for Spinal Cord Injury Treatment Identified

Wrap Around Spinal Cord Device May Transform Injury Treatment

Spinal Injuries Trigger Metabolic Disorders

Stem Cells Spark Hope in Spinal Cord Recovery

Blurry Beginnings Shape Brain’s Visual Pathways

Human Brains Keep Making Memory Neurons in Adulthood

Gene Therapy Restores Hearing in Those with Deafness

Forever Chemicals May Disrupt Brain Development

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