Fenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.
Exoskeletons that help those with spinal cord injuries to walk may help to improve bowel function.
A newly developed hydrogel scaffold with regularly spaced pores assists in spinal cell growth and neuron regeneration following spinal cord injury.
Researchers modified NG2 glial cells in the central nervous system into new neurons to promote recovery following spinal cord injury.
Both the ApoE genotype and the sex of the mouse impacted the manner in which the animals with spinal cord injury responded to hypoxia treatment. Females with the ApoE e4 gene had a negative response to intermittent hypoxia.
Injecting a patient's own bone marrow derived stem cells significantly improved motor function within weeks in those with spinal cord injuries.
People with spinal cord injuries have the same brain activity during processing speed tasks as healthy older adults. The findings suggest the theory of accelerated cognitive aging following SCI is correct.
Research shows it is possible to stimulate stem cells in the spinal cord to produce large amounts of new oligodendrocytes.
Axon regeneration and dramatic improvements in functional recovery occurred when lactate was applied to damaged neural tissue. Treatment with lactate also significantly improved locomotion and restored some walking capability in mouse models of SCI.
The application of synchronized transcranial magnetic stimulation (TMS) and peripheral nerve stimulation (PNS) restored the ability to walk in a patient with spinal cord injury.
A new osmotic transport device removes fluid from the spinal cord to reduce swelling in rat models of SCI.
Researchers implanted specialized neural stem cell grafts directly into mice with spinal cord injuries. As the grafts grew, they integrated with and mimicked the animal's existing neural network.
