Spinal cord injuries cause stem cells in the bone marrow to rapidly divide. Following the cell division, the stem cells become trapped in the bone marrow.
LIN28, a molecule that regulates cell growth could help in the treatment of spinal cord injury and optic nerve damage. When expressed above normal levels, the molecule fuels axon growth in mice with injury, enabling the body to repair damaged nerves.
Researchers were able to restore the sense of touch to a 28-year-old who suffered a spinal cord injury with the help of new brain-computer interface technology.
People who experience a spinal cord injury have an increased risk of developing a mental health disorder, a new study reports. Those with SCI had higher instances of anxiety, depression, and psychological multimorbidity than those who had not experienced a debilitating injury.
Administering nimodipine to mouse models of spinal cord injury reduced spasticity in the animals.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.
Researchers have developed a new method for delivering neural precursor cells into rat models of spinal cord injury. The method is safe, effective, and reduces the likelihood of further spinal trauma while delivering larger doses of reparative stem cells. The new approach could also be used for the treatment of ALS and multiple sclerosis.
A new study challenges existing theories about spinal cord neurons. New findings suggest neurological signals originate from a major, scattered network of cells that send signals to only a few other neurons.
Severed axonal segments signal to Schwann cells to begin actin sphere formation and axon disintegration. If the process is disrupted, axon disintegration is slowed and axon fragments impair nerve regeneration.
A novel surgical technique that connects functioning nerves with injured nerves helps restore function to paralyzed muscles. Following surgery, 13 young adults with tetraplegia now have restored hand and elbow function, allowing them to feed themselves, hold a drink and write.
Researchers have developed a novel 3D printed scaffolding that mimics natural anatomy and boost stem cell treatment for spinal cord repair. While the initial scaffolds have been designed for rat models of SCI, researchers report the approach is scalable to humans.