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Schizophrenia

·July 27, 2023·4 min read

Amotivation and Anhedonia Key to Social Functioning in Schizophrenia

Amotivation and anhedonia, rather than expressive dysfunction, are crucial to determining the social functioning of individuals with schizophrenia. The transdiagnostic network analysis examined the relationship between negative symptoms, other psychopathologies, and social functioning in patients with schizophrenia, major depressive disorder, and bipolar disorder.

Featured Neuroscience Psychology

·July 18, 2023·4 min read

Study Challenges Longstanding Beliefs About Action of Antipsychotic Medications

Researchers uncovered a pivotal detail that could revolutionize schizophrenia treatment. Contrary to longstanding belief, antipsychotic drugs that mitigate overactive dopamine, a hallmark of schizophrenia, interact primarily with a different type of neuron than originally assumed.

Featured Genetics Neuroscience Psychology

·July 6, 2023·5 min read

Schizophrenia Linked to Non-Inherited Genetic Mutations

Researchers found a link between schizophrenia and somatic copy-number variants, mutations occurring post-inheritance. The study scrutinized genotype-marker data from over 20,000 blood samples, identifying two genes, NRXN1 and ABCB11, that correlate with schizophrenia when disrupted during development.

Featured Neuroscience Psychology

·June 2, 2023·4 min read

Shaping Young Minds: Neurodevelopment Interventions for Psychiatric Disorders

Researchers explored potential treatments for neuropsychiatric disorders like schizophrenia and autism that act during critical windows of brain development. They specifically targeted underperforming dopamine neurons, which connect to the frontal cortex and are vital for cognitive processing and decision-making.

Featured Neuroscience Psychology

·June 1, 2023·4 min read

Unexpected Role of Immune Autoantibodies in Schizophrenia

The researchers identified autoantibodies against the synaptic protein neurexin 1α in about 2% of patients with schizophrenia.

Featured Neuroscience Psychology

·May 27, 2023·4 min read

Vitamin D’s Crucial Role in Dopamine Function and Schizophrenia

Neuroscientists discovered how vitamin D deficiency impacts the development of neurons, contributing to disorders such as schizophrenia. Using innovative technology, they were able to observe that a lack of vitamin D not only changes neuron growth but also affects the brain's dopamine release mechanism. They found dopamine release was enhanced in cells grown in the presence of vitamin D, compared to a control.

Featured Neuroscience Psychology

·May 25, 2023·6 min read

Understanding Delusions of Control: How Schizophrenia Alters Perception of Action

A new study sheds light on the phenomenon of 'delusions of control', often experienced by schizophrenia patients. This condition, marked by the belief that one's actions are controlled by external forces, is linked to an altered perception of the time between actions and their outcomes.

This shows two stills of a person's head.

Featured Genetics Neuroscience Psychology

·May 21, 2023·5 min read

Shared Genetics for Cannabis Use and Psychiatric Disorders

Researchers discovered shared genetic underpinnings for cannabis use and psychiatric disorders like schizophrenia and bipolar disorder. Employing advanced statistical modelling, the study revealed a complex interplay of genetic variants increasing or decreasing risk factors for these conditions. These findings may contribute to personalized preventive measures and interventional strategies.

This shows the outline of a head and a brain.

Featured Genetics Neuroscience Psychology

·May 15, 2023·5 min read

Schizophrenia Risk Genes: Placenta’s Role May Outweigh Brain’s

In a paradigm shift, researchers found over 100 genes associated with schizophrenia risk operate primarily through their role in the placenta, rather than the developing brain. The research emphasizes the placenta's significance in illness development, challenging the century-old assumption that genes for schizophrenia risk primarily affect the brain.

Featured Neuroscience Psychology

·May 12, 2023·7 min read

Synaptic Clues Blur Line Between Schizophrenia and Bipolar Disorder

Researchers found compelling molecular evidence suggesting that bipolar disorder and schizophrenia, traditionally viewed as distinct conditions, may have more similarities than previously thought. By examining thousands of proteins present at synapses in the brains of patients with each disorder, they found changes that were remarkably alike. The team also discovered similar biochemical alterations in mice with a mutated gene linked to both conditions. The study reveals the shared molecular roots of these conditions and points to the synapse as a critical area of study for psychiatric disorders.

Featured Neuroscience Psychology

·May 6, 2023·7 min read

Cannabis Use Disorder Linked to Increased Schizophrenia Risk in Males

A new study finds that young men with cannabis use disorder are at an increased risk of developing schizophrenia. The study, which analyzed health records data of more than 6 million people in Denmark, estimated that up to 30% of schizophrenia cases among young men aged 21-30 might have been prevented by avoiding cannabis use disorder, highlighting the need for preventative measures and treatments for cannabis use disorder and schizophrenia.

Featured Neuroscience Psychology

·April 29, 2023·4 min read

Schizophrenia Identified in 60 Seconds via Visual Fixation

Researchers have identified spatial and temporal abnormalities in spontaneous fixational saccades as a potential biomarker for cognitive and positive symptoms in schizophrenia. Researchers combined patient data of fixational eye movement recorded over 60 seconds with machine learning technology, which was able to determine schizophrenia with 85% accuracy. This discovery suggests that fixational saccades could serve as an easily obtainable complementary diagnostic tool for the condition.

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Schizophrenia

Amotivation and Anhedonia Key to Social Functioning in Schizophrenia

Study Challenges Longstanding Beliefs About Action of Antipsychotic Medications

Schizophrenia Linked to Non-Inherited Genetic Mutations

Shaping Young Minds: Neurodevelopment Interventions for Psychiatric Disorders

Unexpected Role of Immune Autoantibodies in Schizophrenia

Vitamin D’s Crucial Role in Dopamine Function and Schizophrenia

Understanding Delusions of Control: How Schizophrenia Alters Perception of Action

Shared Genetics for Cannabis Use and Psychiatric Disorders

Schizophrenia Risk Genes: Placenta’s Role May Outweigh Brain’s

Synaptic Clues Blur Line Between Schizophrenia and Bipolar Disorder

Cannabis Use Disorder Linked to Increased Schizophrenia Risk in Males

Schizophrenia Identified in 60 Seconds via Visual Fixation

Machine Learning Doubles Depression Remission Rate

Structured Programs Physically Slow Down Biological Aging

Large Rewards Accelerate Learning Speed by Extending Brain Signals

Broken Sleep Rhythms: The Glymphatic Link to Dementia

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