VPM1002, a vaccine candidate based on the tuberculosis BCG vaccine, may be effective in protecting against COVID-19. Previous studies in mice have shown the BCG vaccine is effective at protecting against several respiratory viral infections. If effective against coronavirus, researchers hope the vaccine can bridge the time gap until a specific SARS-CoV-2 vaccine is available.
As many as one in three COVID-19 patients report smell loss as an early symptom of the infection. Researchers say the loss of smell could be used as a key clinical indicator of infection in otherwise symptom-free or pre-symptomatic carriers of coronavirus.
Researchers report they have identified a vaccine candidate for COVID-19 and are working towards phase one clinical testing. A chimpanzee adenovirus vaccine vector was chosen as the most suitable vaccine technology for SARS-CoV-2 as it can generate a stronger immune response in one dose and is not a replicating virus.
Researchers have decoded the 3-D architecture of the main SARS-CoV-2 protease. The protein is involved in the reproduction of the virus. The findings may help in the systematic development of drugs to inhibit the reproduction of the virus, potentially lowering COVID-19 infections.
Researchers have launched a new interactive tool that compares hospital capacity with projected demand throughout the nation's 306 hospital regions. The app provides a clear picture of best and worst scenarios across each region for hospital capacity during the COVID-19 pandemic.
Stress, loneliness, and sleep loss can weaken the immune system, leaving people more susceptible to COVID-19. The best way to mitigate the negative health effects of stress and social isolation during the pandemic is to stay connected with others, particularly via video calls.
Researchers have identified a potential new drug target for COVID-19. The scientists mapped the anatomical structures of two critical SARS-CoV-2 proteins in the nsp10/nsp16 complex. If a drug can be developed to inhibit nsp10/nsp16, researchers believe the immune system should be able to detect the infection and eradicate it faster.
Researchers have developed a portable surveillance device that uses machine learning to detect coughing and crowd size in real-time. The system can use the data to directly monitor flu-like illnesses, community trends, and virus spread potential. The system could help monitor the spread of infection and provide a public health response during an epidemic.
Many of us feel obligated to perform acts for loved ones, such as calling more frequently or running an errand for an elderly friend, during this time of social distancing. Researchers report low-level obligations and acts of kindness can help strengthen relationships, while more substantive obligations can put a strain on relationships.
Researchers stress the importance of understanding how COVID-19 affects children to model the pandemic accurately, as well as limiting the disease spread and ensuring younger patients get the help they need.
NYU and FAS researchers have developed a new, interactive website that allows users to ask professionals about COVID-19. If a user has a specific question, they can submit it to a crowdsourced network of doctors and researchers. Questions are currently answered within hours, but as the network grows, it is hoped the timeframe will be shorter. The service will also be available on Amazon's Alexa by the end of the week.