Salk Institute

This shows CA3 neurons

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder.... Read More...
This shows neurons in the DRG

Scratching the surface of how your brain senses an itch

Researchers identified a set of neurons in the spinal cord that transmits a light-touch signal from the skin to the brain. NPY-Y1 signaling regulates the transmission of innocuous tactile information by establishing thresholds for touch discrimination and mechanical itch reflexes. The findings shed new light on the neurobiological basis of chronic itching.... Read More...