Microglia creates dense-core plaques which help to clear away more wispy plaques from neurons, preventing cell death. Findings suggest the dense-core plaques play a defensive role in protecting the brain from the ravages of neurodegenerative diseases, such as Alzheimer's.
Researchers have identified a strain of E.coli in the guts of female mice that cause them to neglect their offspring. The study shows a direct link between the microbiome and maternal behavior.
A new AI model mimics how the prefrontal cortex uses gating to control information flow between different areas of neurons. The system could help in the development of new artificial intelligence technologies that better mimic the human brain.
CMS121, a synthesized variant of fisetin, a chemical found in fruits and vegetables, improved memory, and slows neurodegeneration in mouse models of Alzheimer's disease.
Study shows how sex-determining genes can mediate courtship and aggressive behaviors in fruit flies. The findings demonstrate the complexity of the relationship between behavior and sex.
Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder.