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Salk Institute

Featured Genetics Neurology Pain

·October 17, 2017·3 min read

‘Busybody’ Protein May Get On Your Nerves, But That’s A Good Thing

Researchers have identified a protein that is critical for pain signaling.

Featured Neuroscience Neuroscience Videos Open Neuroscience Articles

·May 5, 2017·6 min read

“Exercise in a Pill” Boosts Athletic Endurance By 70 Percent

Chemical compound mimics the beneficial effects of exercise, including fat burning and increasing stamina, a new study reports.

Featured Neuroscience Neuroscience Videos Open Neuroscience Articles

·November 15, 2016·4 min read

“Princess Leia” Brainwaves Help Sleeping Brain Store Memories

Newly discovered rotating waves of brain activity that repeat during the night are responsible for forming associations between different aspects of a day's memories, a new study reports.

Featured Neuroscience

·December 12, 2022·3 min read

A Compound That Reverses Gut Inflammation Developed

Researchers have developed a new compound, dubbed FexD, that can prevent and reverse inflammation in mouse models of inflammatory bowel disease.

Featured Genetics Neuroscience

·June 6, 2017·4 min read

A Star is Born: Lesser Known Brain Cells Take Center Stage

Researchers have derived a new method for deriving astrocytes from stem cells, opening the door to new research into neuroinflammatory diseases.

Featured Neuroscience

·June 23, 2022·5 min read

A Surprising Link Between Immune System and Hair Growth

Regulatory T cells interact with skin cells using glucocorticoid hormones to generate new hair follicles and promote hair growth. The findings could have positive implications for the development of new therapies to treat alopecia and other hair loss disorders.

Featured Neuroscience

·January 25, 2022·4 min read

Active Ingredient in Cannabis Protects Aging Brain Cells

Cannabinol, an active ingredient in cannabis, can help protect brain cells from oxidative damage and preserve mitochondrial function.

Featured Neuroscience Open Neuroscience Articles

·October 6, 2021·9 min read

Advancing Efforts to Treat, Prevent and Cure Brain Disorders

Collaborative work on the brain atlas describes how different cells are organized and connected throughout the mouse brain. Understanding what differentiates brain cells can lead to new research and potential therapies for brain disorders.

This is a drawing of a chat bubble with a woman typing to a robot

Featured Neuroscience

·March 6, 2023·5 min read

AI Chatbot ChatGPT Mirrors Its Users to Appear Intelligent

According to researchers, language model AIs like ChatGPT reflect the intelligence and diversity of the user. Such language models adopt the persona of the user and mirror that persona back.

Electrophysiology Featured Neuroscience Psychology

·February 19, 2020·5 min read

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder.

Featured Neurology Neuroscience Open Neuroscience Articles

·December 10, 2019·4 min read

Alzheimer’s drug candidates reverse broader aging

CMS121 and J147, two drug candidates that improve memory and slow neurodegeneration associated with Alzheimer's disease, also slow aging in healthy, older mice. The compounds block damage to neurons caused by general aging and restore levels of specific molecules to those seen in younger animals.