FeaturedGeneticsNeuroscience·June 10, 2025·4 min readHow the Brain’s RNA Rings Are FormedCircular RNAs (circRNAs) are stable, ring-shaped molecules that play crucial roles in brain development, cognition, and long-term cellular regulation. Unlike typical RNA, they form closed loops that resist degradation, making them ideal for neurons.Read More
FeaturedGeneticsNeurosciencePsychology·May 22, 2025·4 min readBlood Test Identifies Depression Risk in TeenagersSummary: Researchers have identified nine blood-based microRNAs that are elevated in teens diagnosed with depression, offering a potential biomarker for...Read More
FeaturedGeneticsNeurologyNeuroscience·November 3, 2024·3 min readRNA Structures Linked to Parkinson’s Protein AggregatesResearchers have identified unique RNA structures called G-quadruplexes (G4s) that promote harmful α-synuclein protein aggregation linked to neurodegenerative diseases like Parkinson’s. Elevated calcium levels trigger these G4s, acting as "scaffolds" for α-synuclein clumping. Administering 5-aminolevulinic acid (5-ALA) to model mice prevented aggregation and reduced motor symptoms. This breakthrough suggests that G4-targeted therapies could offer early intervention for neurodegenerative diseases.Read More
FeaturedGeneticsNeuroscience·October 31, 2024·6 min readHow Brain Proteins Shape Neural ConnectionsA new study links hundreds of brain proteins to differences in how brain regions communicate, revealing how microscale molecules can influence macroscale brain connectivity. Researchers studied brain samples and scans from elderly participants to map biochemical mechanisms affecting structural and functional connectivity in the brain. By integrating protein and RNA data with neuroimaging, they identified key proteins associated with communication between brain areas.Read More
FeaturedNeuroscience·October 9, 2024·5 min readAI Discovers 161,000 New VirusesA novel study study using AI has uncovered 161,979 new RNA viruses, significantly expanding our understanding of Earth's viral diversity. These discoveries were made by analyzing genetic data using a machine learning model, which identified previously unrecognized viruses hidden in public databases.Read More
FeaturedGeneticsNeuroscience·September 5, 2024·2 min readRNA Therapy Improves Memory and Reduces AnxietyAn RNA-based therapy, COG-201, can enhance memory and reduce anxiety in animal models by targeting the serotonin 5-HT2A receptor. Scientists found that decreasing this receptor’s expression led to improved cognitive function and reduced anxiety-like behaviors in mice and rats.Read More
FeaturedGeneticsNeurologyNeuroscience·January 18, 2024·5 min readRNA Interference Plays Key Role in Alzheimer’s DiseaseA new study suggests that RNA interference plays a crucial role in the disease. Researchers discovered that aging and Alzheimer’s-affected brains have an imbalance between toxic and protective short RNAs (sRNAs), leading to brain cell death and DNA damage.Read More
FeaturedGeneticsNeurosciencePsychology·November 30, 2023·5 min readRNA’s Pivotal Role in Fear Memory and PTSD TreatmentResearchers have revealed a groundbreaking role of RNA in fear-related learning and memory. Their study shows how noncoding RNA Gas5 influences neuronal excitability, impacting learning and memory processes.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·March 8, 2023·4 min readModifying Messenger RNA May Provide a New Target for Alzheimer’s DiseaseTargeting and reducing the methylation of a key mRNA promoted the migration of macrophages in the brain and can improve cognitive symptoms of Alzheimer's disease.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·March 7, 2023·4 min readBlood Test for Anxiety DevelopedA newly developed blood test screens for biomarkers associated with anxiety to determine a person's risk of developing the disorder as well as monitor the severity of symptoms in those with anxiety.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·February 10, 2023·4 min readCocaine Use Disorder Alters Gene Networks of Neuroinflammation and Neurotransmission in HumansCocaine use disorder alters gene expression in the nucleus accumbens and caudate nucleus, brain areas associated with reward, and the mediation of habit formation.Read More
FeaturedGeneticsNeurologyNeuroscience·February 6, 2023·5 min readOverlooked Tau-RNA Interaction May Play Key Role in DementiaThe interaction of Tau with RNA is a key stage in the development of Alzheimer's disease and other dementias.Read More
