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retinitis pigmentosa

Featured Genetics Neuroscience Visual Neuroscience

·April 26, 2023·3 min read

Gene Therapy for Dogs With Inherited Blinding Eye Disease Set for Human Trials

A groundbreaking gene therapy proven successful in treating an inherited, blinding eye disease in dogs is now poised for clinical trials in humans with the rare condition retinitis pigmentosa. The therapy, which halts vision loss by introducing a normal copy of the CNGB1 gene, could potentially benefit around 2 million people affected worldwide.

Featured Genetics Neurology Neuroscience

·April 20, 2023·5 min read

Engineered Cells Offer Promise for Treating ALS and Blinding Diseases

Engineered stem cells may lead to personalized treatments for a range of neurological and visual disorders, a new study reports. Transplanting engineered induced pluripotent stem cells into the eyes of rodents with retinal degeneration led to the protection of cells in the eyes that support vision. In ALS models, transplanting cells into the spinal cord protected movement controlling cells. The engineered cells also created astrocytes and did not result in tumor formation.

Featured Genetics Neuroscience Visual Neuroscience

·April 14, 2023·4 min read

Stem Cell Therapy Could Restore Vision to Those With Macular Degeneration and Other Blinding Eye Diseases

A new method enables the production of photoreceptor progenitor cells that resemble embryonic cells. These cells can be transplanted and restore retinal function, and ultimately recovery of vision for those with blinding diseases including age-related macular degeneration and retinitis pigmentosa.

Featured Genetics Neuroscience Visual Neuroscience

·March 17, 2023·3 min read

CRISPR Gene-Editing Technique Reverses Vision Loss in Mice

Using a highly versatile form of CRISPR gene editing, researchers successfully restored vision in mice with retinitis pigmentosa.

Featured Neuroscience Visual Neuroscience

·March 20, 2022·7 min read

Antabuse May Help Revive Vision in People With Progressive Blinding Disorders

Antabuse, a drug commonly prescribed to treat alcohol use disorder, may help to restore eyesight in people with genetic retinitis pigmentosa and other disorders associated with retinal degeneration.

This shows how C3 microglia acts to resolve RP

Featured Neurology Neuroscience Visual Neuroscience

·June 17, 2019·4 min read

Immune system can slow degenerative eye disease: Mouse study

Study reveals C3, which can cause damage in some eye diseases, may help to slow the progression of retinitis pigmentosa.

Featured Genetics Neuroscience Open Neuroscience Articles Visual Neuroscience

·March 17, 2019·8 min read

With single gene insertion, blind mice regain sight

Gene therapy that targets retinal ganglion cells with light-sensitive cone opsins helps restore vision in mice. Researchers report a potential human treatment could be available within three years.