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pyramidal neurons

·June 18, 2020·4 min read

How chandelier cells light up the brain

Chandelier cells have an unusual direct method of communication. Unlike other neurons, chandelier cells connect directly to the part of a target neuron that initiates a spike.

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·June 12, 2020·3 min read

Inhibitory interneurons in hippocampus excite the developing brain

GABAergic interneuron excitation is essential for network activity in the hippocampus of the fetal brain.

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·March 9, 2020·4 min read

Brain-doping produced by your own body

Cognitive challenges trigger a slight oxygen deficit in hippocampal pyramidal neurons. This increases the production of erythropoietin (Epo) and its receptors in the active neurons, stimulating neighboring precursor cells to form new neurons and enhancing connectivity.

Electrophysiology Featured Neuroscience Psychology

·February 19, 2020·5 min read

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder.

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·February 4, 2020·4 min read

Unique neuron that computes like a compass identified

Researchers have identified a distinct excitatory neuron in the retrosplenial cortex that encodes direction related information over long durations.

Featured Genetics Neuroscience

·January 8, 2020·4 min read

Abnormal neuron activity manifests as parental neglect

Abnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect.

Autism Featured Genetics Neuroscience

·July 26, 2019·3 min read

Brain region linked to altered social interactions in autism model

The anterior cingulate cortex (ACC) plays a critical role in regulating social behaviors. In mouse models of ASD, dysfunction in the ACC was linked to social impairments associated with the disorder.

Electrophysiology Featured Neuroscience Neuroscience Videos

·June 18, 2019·5 min read

The fractal brain, from a single neuron’s perspective

Researchers say measuring signals from a single neuron may be as good as capturing information from many neurons at once.

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·June 13, 2019·4 min read

Researchers identify hidden brain signals behind working memory

Artificially prolonging hippocampal sharp wave ripples improves working memory.

The illustration is of pyramidal neurons in a rat's neocortex

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·March 21, 2019·4 min read

Blue Brain solves a century-old neuroscience problem

A mathematical algorithm developed by the Blue Brain Project can objectively classify different shapes of neurons in the brain. The algorithm has already helped researchers objectively identify 17 types of pyramidal neurons in the somatosensory cortex of a rat.

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·February 13, 2019·5 min read

Uncovering the Evolution of the Brain

Researchers have developed a new technique to study the development of human neurons compared to the neurons of nonhuman primates. The findings shed new light on the evolution of the human brain.

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·January 14, 2019·1 min read

Memory of Last Meal Influences How Much is Eaten Next: Rat Study

Researchers have identified neurons in the brains of rats that control future food intake by preserving memories of past meals. The findings suggest boosting meal memories could help to manage overeating and curb obesity.