Study reveals the role the mouse gene Ophn1 plays in helpless behaviors and identified three methods in which to reverse the effect. Read More
Area 32, a region of the anterior cingulate, balances activity from cognitive and emotional areas of the primate brain. Read More
Results from a new study implicate the ventromedial thalamus in cost-benefit decision making. Read More
Researchers have identified a new mechanism of learning that stabilizes memory and reduces interference between different memories. Read More
Chandelier cells have an unusual direct method of communication. Unlike other neurons, chandelier cells connect directly to the part of a target neuron that initiates a spike. Read More
GABAergic interneuron excitation is essential for network activity in the hippocampus of the fetal brain. Read More
Cognitive challenges trigger a slight oxygen deficit in hippocampal pyramidal neurons. This increases the production of erythropoietin (Epo) and its receptors in the active neurons, stimulating neighboring precursor cells to form new neurons and enhancing connectivity. Read More
Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder. Read More
Researchers have identified a distinct excitatory neuron in the retrosplenial cortex that encodes direction related information over long durations. Read More
Abnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect. Read More
The anterior cingulate cortex (ACC) plays a critical role in regulating social behaviors. In mouse models of ASD, dysfunction in the ACC was linked to social impairments associated with the disorder. Read More
Researchers say measuring signals from a single neuron may be as good as capturing information from many neurons at once. Read More
