Chandelier cells have an unusual direct method of communication. Unlike other neurons, chandelier cells connect directly to the part of a target neuron that initiates a spike. Read More
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GABAergic interneuron excitation is essential for network activity in the hippocampus of the fetal brain. Read More
Cognitive challenges trigger a slight oxygen deficit in hippocampal pyramidal neurons. This increases the production of erythropoietin (Epo) and its receptors in the active neurons, stimulating neighboring precursor cells to form new neurons and enhancing connectivity. Read More
Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder. Read More
Researchers have identified a distinct excitatory neuron in the retrosplenial cortex that encodes direction related information over long durations. Read More
Abnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect. Read More
The anterior cingulate cortex (ACC) plays a critical role in regulating social behaviors. In mouse models of ASD, dysfunction in the ACC was linked to social impairments associated with the disorder. Read More
Researchers say measuring signals from a single neuron may be as good as capturing information from many neurons at once. Read More
Artificially prolonging hippocampal sharp wave ripples improves working memory. Read More
A mathematical algorithm developed by the Blue Brain Project can objectively classify different shapes of neurons in the brain. The algorithm has already helped researchers objectively identify 17 types of pyramidal neurons in the somatosensory cortex of a rat. Read More
Researchers have developed a new technique to study the development of human neurons compared to the neurons of nonhuman primates. The findings shed new light on the evolution of the human brain. Read More
Researchers have identified neurons in the brains of rats that control future food intake by preserving memories of past meals. The findings suggest boosting meal memories could help to manage overeating and curb obesity. Read More
