Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder.
Researchers have identified a distinct excitatory neuron in the retrosplenial cortex that encodes direction related information over long durations.
Abnormal activation of parvalbumin neurons in the young mouse auditory cortex manifests as a result of maternal neglect.
The anterior cingulate cortex (ACC) plays a critical role in regulating social behaviors. In mouse models of ASD, dysfunction in the ACC was linked to social impairments associated with the disorder.
Researchers say measuring signals from a single neuron may be as good as capturing information from many neurons at once.
Artificially prolonging hippocampal sharp wave ripples improves working memory.
A mathematical algorithm developed by the Blue Brain Project can objectively classify different shapes of neurons in the brain. The algorithm has already helped researchers objectively identify 17 types of pyramidal neurons in the somatosensory cortex of a rat.
Researchers have developed a new technique to study the development of human neurons compared to the neurons of nonhuman primates. The findings shed new light on the evolution of the human brain.
Researchers have identified neurons in the brains of rats that control future food intake by preserving memories of past meals. The findings suggest boosting meal memories could help to manage overeating and curb obesity.
A new study reveals the role synaptic feedback systems play in shaping learning processes. The findings could help develop more efficient artificial intelligence techniques.
Researchers have identified a mechanism within the cholinergic system that underlies our ability to rapidly focus attention.
The thickness of the brain's neocortex influences how individual neurons process information, a new study reveals.