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psychopharmacology

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Featured Neuroscience Psychology Visual Neuroscience

·April 22, 2025·4 min read

Psychedelics Linked to Visual Echoes

As psychedelics gain traction in mental health treatment, questions remain about their long-term effects. A new study followed individuals self-administering psychedelics and found that while some experienced lingering visual aftereffects, most were not distressed by them.

Featured Neuroscience Psychology

·April 14, 2025·5 min read

LSD-Inspired Drug Reverses Psychosis Brain Damage Without Hallucinations

A new LSD-derived compound called JRT shows promise for treating schizophrenia and other brain disorders without inducing hallucinations. Developed by researchers who altered just two atoms in LSD’s structure, JRT maintains the psychedelic’s neuroplastic effects while avoiding its psychosis-linked risks.

Featured Neurology Neuroscience Psychology

·April 7, 2025·7 min read

ADHD Drugs Linked to Heart Effects

A large new analysis of 102 clinical trials finds that ADHD medications have overall small effects on blood pressure and heart rate in both children and adults. These cardiovascular effects—mostly modest increases—were consistent across stimulants and non-stimulants, with guanfacine being the exception, lowering these parameters.

Featured Neuroscience Psychology

·April 4, 2025·3 min read

How Psilocybin Lifts Mood Without the Hallucinogenic Trip

Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial frontal cortex and the serotonin 5-HT2A receptor as essential to the therapeutic action of psilocybin.

Featured Neuroscience Psychology

·March 31, 2025·5 min read

Psychedelics May Enhance Intimacy, Attraction, and Sexual Expression

In the first study of its kind, researchers found that psychedelic use can positively affect sexuality, romantic relationships, and gender expression. Surveying nearly 600 users of substances like psilocybin, LSD, and ketamine, the study revealed that many participants reported increased partner attraction, improved intimacy, and enhanced sexual experiences.

Featured Neuroscience Psychology

·February 25, 2025·3 min read

SSRIs May Speed Up Cognitive Decline

A new study based on data from 18,740 dementia patients suggests that antidepressants may accelerate cognitive decline. Researchers found that patients taking antidepressants, particularly SSRIs like escitalopram, citalopram, and sertraline, experienced faster deterioration compared to those not on medication.

Featured Neuroscience Psychology

·February 23, 2025·3 min read

Repurposed Blood Pressure Drug May Treat ADHD

A new study suggests that amlodipine, a widely used blood pressure medication, could help manage ADHD symptoms. Researchers tested five potential drugs in rats bred for ADHD-like behaviors, and only amlodipine significantly reduced hyperactivity.

Featured Neuroscience Psychology

·February 14, 2025·4 min read

How Ketamine Binds to Brain Receptors to Alter Mood

New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds to this receptor, revealing multiple attachment sites that influence brain activity.

Featured Neuroscience Psychology

·February 14, 2025·6 min read

Prozac Shows Promise in Fighting Infections & Sepsis

New research suggests that fluoxetine, commonly used as an antidepressant, may also help protect against infections and sepsis. Scientists found that the drug has antimicrobial properties and helps regulate the immune response, reducing the risk of tissue and organ damage.

Autism Featured Genetics Neuroscience

·December 27, 2024·5 min read

Lithium Restores Brain Function and Behavior in Autism

Lithium, a drug widely used for bipolar disorder, may also treat autism spectrum disorder (ASD), according to new research. The study found that lithium restored brain function and reduced behavioral symptoms in mice with Dyrk1a gene mutations, a known ASD risk factor.

Featured Neuroscience Psychology

·December 17, 2024·6 min read

Ketamine Reduces “Giving Up” by Targeting Brain Support Cells

Researchers have found that ketamine’s antidepressant effects target astroglia, a type of brain support cell, rather than neurons, challenging conventional views. Using zebrafish, scientists observed that ketamine suppressed the “giving up” behavior caused by futility signals, an effect linked to astroglial activation.

Featured Neuroscience Psychology

·December 12, 2024·8 min read

Gut Serotonin Plays Role in Depression and Mood

Serotonin in the gut epithelium plays a critical role in modulating mood and may provide a safer target for treating depression and anxiety. In animal studies, increasing gut serotonin improved mood symptoms without causing digestive issues, unlike systemic antidepressant treatments.

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psychopharmacology

Psychedelics Linked to Visual Echoes

LSD-Inspired Drug Reverses Psychosis Brain Damage Without Hallucinations

ADHD Drugs Linked to Heart Effects

How Psilocybin Lifts Mood Without the Hallucinogenic Trip

Psychedelics May Enhance Intimacy, Attraction, and Sexual Expression

SSRIs May Speed Up Cognitive Decline

Repurposed Blood Pressure Drug May Treat ADHD

How Ketamine Binds to Brain Receptors to Alter Mood

Prozac Shows Promise in Fighting Infections & Sepsis

Lithium Restores Brain Function and Behavior in Autism

Ketamine Reduces “Giving Up” by Targeting Brain Support Cells

Gut Serotonin Plays Role in Depression and Mood

Central Genetic Switch Controls Long-Distance Axon Navigation

Disadvantaged Neighborhoods Linked to Accelerated Brain Aging

Brain Activity Predicts Risky Choices Half a Second Before They Are Made

AI-Designed “Longevity Vaccines” Target the Earliest Culprits of Cellular Aging

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