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psychopharmacology

·April 29, 2025·6 min read

Ketamine’s Hidden Physical and Psychological Damage

A new study highlights the severe physical and psychological consequences linked to ketamine addiction, with many users unaware of the risks until dependent. Researchers found high rates of bladder damage, painful organ cramps, low mood, and anxiety among those with ketamine use disorder.

Featured Neuroscience Psychology

·April 23, 2025·6 min read

Can Brain Scans Tell Which Antidepressant Will Work for You?

A new study shows that brain connectivity patterns, especially in the dorsal anterior cingulate cortex, can help predict how patients with major depressive disorder (MDD) will respond to antidepressants. By combining brain imaging with clinical data, researchers developed machine learning models that accurately predicted treatment outcomes across two large trials.

Featured Neuroscience Psychology

·April 23, 2025·5 min read

Psychedelics May Reset Brain-Immune Link Driving Fear and Anxiety

A new study reveals that chronic stress activates immune cells that travel to the brain, amplify inflammation, and heighten fear responses. Researchers found that psychedelics like MDMA and psilocybin disrupt this immune-brain crosstalk, reducing stress-related fear in mice and showing similar effects in human tissue samples.

Featured Neuroscience

·April 23, 2025·4 min read

Psychedelic Sparks Long-Term Brain Plasticity

A single dose of the psychedelic compound 25CN-NBOH significantly improved cognitive flexibility in mice, with effects lasting up to three weeks post-treatment. Treated mice adapted more quickly in rule-switching tasks, indicating enhanced neuroplasticity in the prefrontal cortex.

Featured Neuroscience Psychology

·April 22, 2025·4 min read

More People Turning to Psilocybin for Self-Treatment

Psilocybin use in the U.S. has risen sharply across all age groups since 2019, coinciding with increasing legalization and interest in its therapeutic potential. A new study reveals a 44% rise in past-year use among young adults and a 188% increase among those over 30.

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Featured Neuroscience Psychology Visual Neuroscience

·April 22, 2025·4 min read

Psychedelics Linked to Visual Echoes

As psychedelics gain traction in mental health treatment, questions remain about their long-term effects. A new study followed individuals self-administering psychedelics and found that while some experienced lingering visual aftereffects, most were not distressed by them.

Featured Neuroscience Psychology

·April 14, 2025·5 min read

LSD-Inspired Drug Reverses Psychosis Brain Damage Without Hallucinations

A new LSD-derived compound called JRT shows promise for treating schizophrenia and other brain disorders without inducing hallucinations. Developed by researchers who altered just two atoms in LSD’s structure, JRT maintains the psychedelic’s neuroplastic effects while avoiding its psychosis-linked risks.

Featured Neurology Neuroscience Psychology

·April 7, 2025·7 min read

ADHD Drugs Linked to Heart Effects

A large new analysis of 102 clinical trials finds that ADHD medications have overall small effects on blood pressure and heart rate in both children and adults. These cardiovascular effects—mostly modest increases—were consistent across stimulants and non-stimulants, with guanfacine being the exception, lowering these parameters.

Featured Neuroscience Psychology

·April 4, 2025·3 min read

How Psilocybin Lifts Mood Without the Hallucinogenic Trip

Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial frontal cortex and the serotonin 5-HT2A receptor as essential to the therapeutic action of psilocybin.

Featured Neuroscience Psychology

·March 31, 2025·5 min read

Psychedelics May Enhance Intimacy, Attraction, and Sexual Expression

In the first study of its kind, researchers found that psychedelic use can positively affect sexuality, romantic relationships, and gender expression. Surveying nearly 600 users of substances like psilocybin, LSD, and ketamine, the study revealed that many participants reported increased partner attraction, improved intimacy, and enhanced sexual experiences.

Featured Neuroscience Psychology

·February 25, 2025·3 min read

SSRIs May Speed Up Cognitive Decline

A new study based on data from 18,740 dementia patients suggests that antidepressants may accelerate cognitive decline. Researchers found that patients taking antidepressants, particularly SSRIs like escitalopram, citalopram, and sertraline, experienced faster deterioration compared to those not on medication.

Featured Neuroscience Psychology

·February 23, 2025·3 min read

Repurposed Blood Pressure Drug May Treat ADHD

A new study suggests that amlodipine, a widely used blood pressure medication, could help manage ADHD symptoms. Researchers tested five potential drugs in rats bred for ADHD-like behaviors, and only amlodipine significantly reduced hyperactivity.

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psychopharmacology

Ketamine’s Hidden Physical and Psychological Damage

Can Brain Scans Tell Which Antidepressant Will Work for You?

Psychedelics May Reset Brain-Immune Link Driving Fear and Anxiety

Psychedelic Sparks Long-Term Brain Plasticity

More People Turning to Psilocybin for Self-Treatment

Psychedelics Linked to Visual Echoes

LSD-Inspired Drug Reverses Psychosis Brain Damage Without Hallucinations

ADHD Drugs Linked to Heart Effects

How Psilocybin Lifts Mood Without the Hallucinogenic Trip

Psychedelics May Enhance Intimacy, Attraction, and Sexual Expression

SSRIs May Speed Up Cognitive Decline

Repurposed Blood Pressure Drug May Treat ADHD

Brain Prioritizes “Sound Offsets” During Hearing Repair

Glucose Levels Signal the Growth of Myelin

Why Your Brain “Dreams” Even When You’re Awake

Mapping the Brain’s Hidden Hub for Creative Thought

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