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psychopharmacology

·March 12, 2023·5 min read

Research Points to Drug Option for Hair-Pulling and Skin-Picking Disorders

Memantine, a drug commonly prescribed to treat symptoms of Alzheimer's disease, reduces symptoms for adults with hair-pulling and skin-picking disorders.

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·February 28, 2023·5 min read

Considering Going Off Antidepressants? Here’s What to Think About First

During the COVID-19 pandemic, there has been an uptick in the use of antidepressant medications to combat symptoms of depression. Researchers discuss the impact of antidepressant usage and provide guidelines for safe and effective withdrawal from antidepressant medications.

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·February 24, 2023·5 min read

Psychedelics May Help People Reinvent Themselves

In addition to helping treat mental health disorders, psychedelic treatments can help people overcome addictions. A new study reports psychedelics can help smokers quit nicotine and remain smoke-free for at least five years.

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·February 23, 2023·6 min read

Mystical and Insightful Psychedelic Experience May Improve Mental Health

Recent studies have explored the use of psychedelics for the treatment of a range of mental health disorders. A new study reveals more insightful and mystical "trips" while exposed to psychedelics may be linked to an enduring reduction of symptoms for those with anxiety and depression.

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·February 21, 2023·5 min read

Medication Targeting Brain Stress Response May Help Cardiovascular Symptoms of Alcohol Withdrawal

Prazosin, an FDA-approved medication for the treatment of hypertension may help to prevent relapse in people with cardiovascular and behavioral symptoms of alcohol withdrawal, a new study reports.

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·February 21, 2023·4 min read

Pill for Skin Disease Also Curbs Excessive Drinking

Apremilast, an FDA-approved drug for the treatment of skin conditions including psoriasis and psoriatic arthritis, triggers increased activity in the nucleus accumbens, a brain area associated with regulating alcohol intake. Apremilast reduced drinking behaviors in mouse models with a genetic risk of alcohol use disorder.

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·February 20, 2023·4 min read

Ketamine Could Be Effective Treatment for Cocaine-Use Disorders

Those with cocaine use disorder who were administered ketamine for depression or pain experienced two-to-four times higher remission rate.

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·February 17, 2023·3 min read

Vasodilator Drug Used in Stroke Patients Found to Reverse Key Symptoms of Schizophrenia

Vasodilators such as fasudil, commonly used for the treatment of stroke, restored pyramidal neurons in the prefrontal cortex of mouse models of schizophrenia associated with genetics.

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·February 16, 2023·3 min read

Receptor Location Matters for Psychedelic Drug Effects

Location bias may explain how psychedelic medications work. Researchers found that engaging serotonin 2A receptors inside neurons promotes the growth of new connections, but engaging the same receptor on the outside of a neuron does not. The findings may guide the development of new psychoplastogens to treat a range of disorders including depression and PTSD.

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·February 14, 2023·4 min read

Drug Shown to Alleviate Autism-Associated Behavior

A newly developed drug that blocks sodium channels in the cell membrane that can reverse MYT1L failure alleviates social behavior deficits in mouse models of ASD.

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·February 2, 2023·7 min read

Antidepressants Use for Chronic Pain on the Rise, but Are They Effective?

SNRI antidepressants appear to be effective in the treatment of a range of pain conditions including neuropathic pain, fibromyalgia, and postoperative pain. Tricyclic antidepressants may not be effective in the treatment of pain.

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·January 31, 2023·5 min read

Beta-Blocker Use Associated With Lower Rates of Violence

Beta-blockers, a class of drugs commonly used to treat hypertension and cardiovascular disorders, appear to reduce aggressive and violent behaviors, and can reduce suicidal behaviors.