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psychopharamcology

This shows a man holding a wine glass against a psychedelic backdrop.

·November 10, 2025·4 min read

Psychedelics Calm Stress Circuits to Reduce Alcohol Drinking

New research shows that psilocin, the active metabolite of the psychedelic psilocybin, may reduce alcohol consumption by calming stress-sensitive neurons in the central amygdala. In female mice exposed to long-term alcohol use, psilocin dampened the hyperactivity of these neurons, temporarily reducing drinking.

This shows a happy person surrounded by psychedelic swirls.

Featured Neuroscience Psychology

·October 8, 2024·3 min read

Optimism Boosted by Psilocybin, Hinting at Depression Relief

Researchers have discovered that psilocybin, a psychedelic compound in magic mushrooms, increases optimism and motivation in rats, suggesting potential therapeutic benefits for treating depression. Using computational modeling, scientists observed that rats given psilocybin were more likely to engage in reward-based tasks, indicating enhanced optimism.

Featured Neuroscience Psychology

·May 30, 2024·6 min read

AI Tool Matches Patients to Effective Antidepressants Faster

Researchers developed an AI-based tool, MeAgainMeds.com, to help match patients with the most effective antidepressants based on their medical history. This free website aims to reduce the trial-and-error process in finding the right medication, improving patient outcomes.

This shows wild psilocybin cyanescens mushrooms

Featured Neuroscience Psychology

·April 16, 2021·8 min read

Psilocybin Performs At Least As Well as Leading Antidepressant in Small Study

Psilocybin, the psychoactive compound found in magic mushrooms, is as effective at treating depression as conventional SSRI antidepressants. Researchers report, that although not significantly significant, early findings reveal those treated with psilocybin experienced more rapid and greater reductions in depression symptoms than those treated with SSRIs.

Featured Neuroscience Psychology

·February 1, 2021·4 min read

Antipsychotic Prescriptions Rising Much Faster Than Psychosis Rates

While England has only seen a moderate rise in people being diagnosed with psychosis in recent years, prescription rates for antipsychotic medications have doubled.

Featured Open Neuroscience Articles Psychology

·August 14, 2020·6 min read

Study Uncovers the Molecular Events by Which Popular Antidepressants Work

Activity of the c-Fos gene begins the increase on the ninth day of exposure to antidepressants. By day 14, mice showed behavioral changes associated with SSRI use. This may explain why suicide rates drop after nine days of treatment, and symptoms of depression improve after three weeks.

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·February 20, 2019·5 min read

Some Drug Combinations More Effective Than Others For Patients with Schizophrenia

A new study reveals some drug combinations may be more beneficial for those with schizophrenia. Researchers found people with schizophrenia who took antidepressants, in combination with other medications, were less likely to be hospitalized for mental health issues than those who started another antipsychotic.

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·July 19, 2018·5 min read

ADHD Drugs Do Not Improve Cognition in Healthy College Students

Researchers report, contrary to popular belief, Adderall and other ADHD drugs do not improve cognition in healthy college students. Instead, they may impair cognitive function.

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·March 15, 2018·5 min read

ADHD Drug Increases Glutamate and Positive Emotion in Healthy People

A new study reveals a psychostimulant prescribed for ADHD increases glutamate in the brains of healthy people, resulting in more positive emotions.

Featured Open Neuroscience Articles Psychology

·June 17, 2016·4 min read

Antidepressant Drug Enhance Feelings of Control in Depression

A new study reports the way antidepressants affect learning about control and helplessness could explain why the therapeutic effects take time, as well as why their effectiveness differs among people.

Image shows the effectiveness of ketamine in treating depression.

Featured Neuroscience Videos Open Neuroscience Articles Psychology

·May 18, 2016·5 min read

How Depression and Antidepressant Drugs Work

A new study shows the effectiveness of ketamine in treating depression in a mouse model of the disease and also helps bring together two hypotheses for the cause of depression.

Featured Psychology

·February 28, 2016·4 min read

Antidepressant May Improve Cognitive Function in HIV Patients

Researchers report the antidepressant paroxetine suppresses neuroinflammation in improves reaction time in people with HIV associated cognitive impairment.