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          protein aggregation

          This shows a rendition of proteins clumping.
          FeaturedGeneticsNeurologyNeuroscience
          ·January 6, 2025·3 min read

          Lipid Anchors Hold Key to Preventing Protein Aggregation in Prion Diseases

          A lipid anchor on nerve cell membranes stabilizes prion proteins (PrPC) and prevents their pathological aggregation into forms linked to prion diseases. Researchers developed new in vitro and cell models to study how membrane anchoring inhibits these harmful transformations.
          Read More
          This shows neurons.
          FeaturedGeneticsNeurologyNeuroscience
          ·April 3, 2024·6 min read

          Cracking Parkinson’s: Proteins’ Aggregation Unveiled

          Researchers employing computational models have made a significant leap in understanding the aggregation of alpha-synuclein protein, crucial in Parkinson’s disease development. This study marks the first to map the molecular dynamics of these proteins in detail, revealing how environmental factors like molecule crowding and ionic changes enhance aggregation.
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          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·November 15, 2022·5 min read

          Slow-Moving Shell of Water Can Make Parkinson’s Proteins ‘Stickier’

          Water plays a key role in how proteins associated with Parkinson's disease fold, clump or misfold.
          Read More
          This shows alpha synuclein build up
          FeaturedNeurologyNeuroscience
          ·July 7, 2022·4 min read

          Copper Leads to Protein Aggregation in Parkinson’s Disease

          Alpha-synuclein proteins form into unusual shapes when exposed to large quantities of copper ions. Researchers say the effect of environmental copper exposure on alpha-synuclein could play a role in the pathogenesis of Parkinson's disease.
          Read More
          This shows a diagram from the study
          FeaturedNeurologyNeuroscience
          ·August 16, 2019·4 min read

          Using math to help treat Alzheimer’s, Parkinson’s and other diseases

          Using control theory and the physics of protein aggregation, researchers created theoretical predictions on how and when to use drug interventions for neurodegenerative diseases.
          Read More
          Photo of an alzheimer's brain.
          Featured
          ·November 3, 2015·5 min read

          Alzheimer’s May Be a Collection of Different Diseases That Should be Treated Separately

          Researchers report Alzheimer's disease may actually be a collection of different disease that should be treated independently with different approaches.
          Read More
          Image shows a DNA double helix.
          FeaturedGenetics
          ·October 30, 2015·3 min read

          Shedding Light on Protein Related Diseases

          Researchers report some proteins turn into liquid droplets on their way to becoming the toxic solids implicated in some neurodegenerative disorders.
          Read More
          The image shows the molecular chaperone binding to amyloid beta.
          FeaturedGenetics
          ·February 17, 2015·5 min read

          Molecular Inhibitor Breaks Cycle That Leads to Alzheimer’s

          A new study reports a molecular chaperone can inhibit a key stage in the development of Alzheimer's disease.
          Read More
          This image shows the aggregates binding to mitochoindria and endoplasmic reticulum.
          FeaturedGeneticsNeuroscience Videos
          ·October 16, 2014·4 min read

          Misfolded Proteins Clump Together in a Surprising Place

          A new study reports researchers have created a new framework for protein aggregation under acute stress.
          Read More

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          This shows an ear.

          Gene Therapy Restores Hearing in Those with Deafness

          This shows a brain.

          Forever Chemicals May Disrupt Brain Development

          This shows kids playing games.

          Kids Outsmart AI in Puzzle Game That Builds Critical Thinking

          This shows a neuron.

          Drug-Coated Neural Implants Reduce Immune Rejection

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