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protein aggregation

This shows a rendition of proteins clumping.

Featured Genetics Neurology Neuroscience

·January 6, 2025·3 min read

Lipid Anchors Hold Key to Preventing Protein Aggregation in Prion Diseases

A lipid anchor on nerve cell membranes stabilizes prion proteins (PrPC) and prevents their pathological aggregation into forms linked to prion diseases. Researchers developed new in vitro and cell models to study how membrane anchoring inhibits these harmful transformations.

Featured Genetics Neurology Neuroscience

·April 3, 2024·6 min read

Cracking Parkinson’s: Proteins’ Aggregation Unveiled

Researchers employing computational models have made a significant leap in understanding the aggregation of alpha-synuclein protein, crucial in Parkinson’s disease development. This study marks the first to map the molecular dynamics of these proteins in detail, revealing how environmental factors like molecule crowding and ionic changes enhance aggregation.

Featured Genetics Neurology Neuroscience

·November 15, 2022·5 min read

Slow-Moving Shell of Water Can Make Parkinson’s Proteins ‘Stickier’

Water plays a key role in how proteins associated with Parkinson's disease fold, clump or misfold.

Featured Neurology Neuroscience

·July 7, 2022·4 min read

Copper Leads to Protein Aggregation in Parkinson’s Disease

Alpha-synuclein proteins form into unusual shapes when exposed to large quantities of copper ions. Researchers say the effect of environmental copper exposure on alpha-synuclein could play a role in the pathogenesis of Parkinson's disease.

$This shows a diagram from the study$

Featured Neurology Neuroscience

·August 16, 2019·4 min read

Using math to help treat Alzheimer’s, Parkinson’s and other diseases

Using control theory and the physics of protein aggregation, researchers created theoretical predictions on how and when to use drug interventions for neurodegenerative diseases.

Featured

·November 3, 2015·5 min read

Alzheimer’s May Be a Collection of Different Diseases That Should be Treated Separately

Researchers report Alzheimer's disease may actually be a collection of different disease that should be treated independently with different approaches.