While 40% of people with primary progressive aphasia have underlying Alzheimer's disease, a new study suggests they may not develop the memory problems associated with Alzheimer's.
Language difficulties associated with primary progressive aphasia differ depending on a person's native language, a new study reports. Native English speakers with PPA have more trouble pronouncing words, while those who speak Italian had fewer pronunciation problems but tend to produce shorter and grammatically simpler sentences.
Researchers have identified the location of dysfunctional brain networks that lead to impaired sentence production and word-finding in primary progressive aphasia (PPA). PPA can occur in those with neurodegenerative diseases, such as frontotemporal dementia and Alzheimer's disease. Mapping the networks allows clinicians to apply non-invasive brain stimulation to potentially improve speech in those with PPA.
Using MEG neuroimaging, researchers identify abnormalities in functional activity in brain regions which look structurally normal on conventional MRI scans. The findings could help with early detection of primary progressive aphasia.
A small, preliminary study helps researchers identify a region of the brain that specializes in the processing of auditory words.
Researchers discover amyloid accumulation is greater on the left side of the brain with many individuals living with PPA.