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          prefrontal cortex

          This shows a head and a brain.
          FeaturedNeurosciencePsychology
          ·May 22, 2025·7 min read

          Potassium Channel Drug Offers New Hope for Treating Depression

          Two new studies reveal that ezogabine, a drug originally approved for epilepsy, may alleviate depression symptoms by targeting potassium channels in the brain. Researchers found that the drug improves function in reward-related brain regions like the ventral tegmental area (VTA), which is key to motivation and pleasure.
          Read More
          This shows a head and sound waves.
          Auditory NeuroscienceFeaturedNeuroscience
          ·May 13, 2025·5 min read

          How the Brain Links Sound to Meaning

          A new study has mapped how the brain retrieves words during speech, identifying two distinct but overlapping networks in the prefrontal cortex. Researchers used high-resolution electrocorticography in 48 patients to reveal that semantic processing and articulatory planning occur in neighboring yet functionally distinct regions.
          Read More
          This shows a woman and a glass of wine.
          FeaturedNeurosciencePsychology
          ·May 4, 2025·12 min read

          Why Alcohol Hits Women Harder

          Alcohol use among women has surged to match men’s rates, but women face far greater health risks even at lower consumption levels. A growing body of research is uncovering key neurobiological sex differences that influence why and how women drink, with stress being a more prominent motivator for women.
          Read More
          This shows a face.
          FeaturedNeuroscience
          ·May 2, 2025·5 min read

          Study Challenges Leading Theories On Consciousness Origins

          A landmark study tested two leading theories of consciousness — Integrated Information Theory (IIT) and Global Neuronal Workspace Theory (GNWT) — but found neither definitively explained conscious experience. While IIT emphasizes deep integration of brain regions and GNWT highlights widespread broadcasting of information, data from 256 human subjects did not fully support either.
          Read More
          This shows two heads.
          FeaturedNeurosciencePsychology
          ·December 12, 2024·4 min read

          Emotional Memory Cells Driving Empathy Discovered

          Researchers have uncovered a brain mechanism in the prefrontal cortex that determines how animals respond to others’ emotions based on their own past experiences. These neurons, producing corticotropin-releasing factor (CRF), act as emotional memories, modulating responses to socio-emotional stimuli.
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          This shows a brain and a person at a bus stop.
          FeaturedNeuroscience
          ·December 10, 2024·7 min read

          Brain’s Quit-or-Wait Dilemma: How We Decide to Persist or Move On

          New research sheds light on how the brain's prefrontal cortex evaluates whether to persist or quit in uncertain situations. Using tasks mimicking real-life dilemmas, researchers found that different brain regions influence patience and adaptability.
          Read More
          This shows a child and brain scans.
          AutismFeaturedNeuroscience
          ·August 22, 2024·4 min read

          Early Brain Changes May Trigger Autism

          Researchers have uncovered critical insights into how autism spectrum disorders (ASD) may develop at early stages of brain formation. Using mouse models, the team discovered that environmental factors causing autism-like symptoms are linked to early changes in neurotransmitter activity in the brain. Specifically, they observed that a temporary switch from the inhibitory neurotransmitter GABA to the excitatory neurotransmitter glutamate in neonatal mice could lead to the development of ASD-like behaviors, such as repetitive actions and reduced social interaction, later in life.
          Read More
          This shows a woman looking at a model of a brain.
          FeaturedNeuroscience
          ·June 7, 2024·4 min read

          Brains’ Decision-Making Mechanism Revealed

          A new study uncovered neural mechanisms used in planning, revealing an interplay between the prefrontal cortex and hippocampus. The study shows how the brain imagines future outcomes to guide decisions. This research sheds light on the cognitive processes behind planning, with potential implications for treating disorders affecting decision-making.
          Read More
          This shows a person's head.
          FeaturedNeuroscience
          ·February 24, 2024·4 min read

          Unlocking the Brain’s Fear Circuitry: A Pathway to Survival Responses

          Scientists have identified a new neural pathway that plays a crucial role in how the brain shifts to high-intensity fear responses. This discovery pinpoints a previously unknown connection between the prefrontal cortex and the amygdala, crucial for emotional regulation and decision-making during fearful situations.
          Read More
          This shows a brain.
          FeaturedNeuroscience
          ·February 1, 2024·5 min read

          How the Brain Crafts Words Before Speaking

          A new study utilizes advanced Neuropixels probes to unravel the complexities of how the human brain plans and produces speech. The team identified specific neurons in the prefrontal cortex involved in the language production process, including the separate neural pathways for speaking and listening.
          Read More
          This shows a colorful brain
          FeaturedNeuroscienceNeuroscience Videos
          ·April 29, 2023·5 min read

          Cognitive Flexibility: How the Brain Learns New Rules to Navigate the Changing World

          In everyday life, our brains adapt to new situations using the prefrontal cortex. A team of neuroscientists discovered a special class of neurons in the prefrontal cortex that enable flexible behavior, and when malfunctioning, may contribute to conditions like schizophrenia and bipolar disorder. These long-range inhibitory connections synchronize gamma oscillations across the left and right prefrontal cortex, allowing the brain to change its behavior at the right moment. This research could lead to new treatments for psychiatric conditions by targeting these long-range inhibitory connections.
          Read More
          This shows DNA and the outline of a person
          FeaturedGeneticsNeurosciencePsychology
          ·April 7, 2023·6 min read

          New Genetic Finding Provides Clue for Personalizing Depression Treatment

          The NPAS4 gene may play a critical role in linking long-term stress to depression and depressive behaviors. The findings may lead to new, targeted treatments for depression as a result of chronic stress.
          Read More
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          Alzheimer’s Risk Linked to Increased Social Activity, Not Isolation

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          How Memory and Habits Shape Mental Health Outcomes

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          Most People Overestimate Their Moral Courage Under Pressure

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          RyR1 Channel Triggers Sedation from Anesthetics

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