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potassium channels

·March 4, 2026·7 min read

Epilepsy Mutations Leave Potassium Channels Stranded

New research reveals that dysfunctional potassium channels fail to reach the brain's "signal tower," explaining why some genetic mutations lead to severe epilepsy.

Featured Neuroscience Open Neuroscience Articles

·October 11, 2022·6 min read

Shaker Channel Mutation Differs Structurally From Human Potassium Channels

Study investigates whether the W434F mutation found in the Shaker-IR channel epitomizes and functionally accelerates the C-type inactivation state.

Electrophysiology Featured Neuroscience

·July 19, 2022·4 min read

Researchers Discover Novel Light-Gated Potassium Channel in Neurons

Researchers report they have identified the first natural light-gated potassium channel-rhodopsins.

Featured Neuroscience Psychology

·May 31, 2022·6 min read

Study Sheds New Light on a Promising Antidepressant

Ketamine's antidepressant effect is a result of the enhancement of Kcnq2 potassium channels in a certain subtype of glutamate-sensitive neurons.

This shows a sad looking man looking out of a window at the rain

Featured Neuroscience Psychology

·March 3, 2021·6 min read

Researchers Identify Brain Ion Channel as New Approach to Treating Depression

Ezogabine, a drug that opens up the KCNQ2/3 type potassium channel, significantly improved symptoms of depression and anhedonia.

Electrophysiology Featured Neuroscience

·February 25, 2020·3 min read

Shining new light on the actions of key neurotransmitter in the brain

GABA can selectively regulate the excitability of neurons.

Featured Neuroscience Psychology

·November 1, 2018·4 min read

Anti-Convulsant Drug Reduces Major Depression Symptoms

Ezogabine, an FDA approved anti-convulsant, appears to significantly reduce symptoms in those with major depressive disorder.

Image shows a cross section of the sensory epithelium of the developing inner ear in a mouse.

Featured Genetics Neurology

·November 27, 2015·6 min read

How Cells in the Developing Ear Practice Hearing

Researchers have discovered a molecular chain of events that enable cells in the inner ear to practice processing sounds during development.

This image shows how light affects the suprachiasmatic nucleus in the circadian cycle.

Featured Neuroscience

·August 13, 2015·4 min read

Mechanism that Controls When We Sleep and When We Wake Discovered

Researchers discover changes in the activity of sodium and potassium channels during the day and night impact the sleep-wake cycle.

This image shows a top view of potassium ions (purple) moving through potassium channel.

Featured Neurology

·June 23, 2015·5 min read

Turning the Ringer Off

Researchers report a new drug could treat epilepsy and help prevent tinnitus by selectively affecting potassium channels.

This image shows a representation of DNA sequencing.

Featured Genetics Neurology

·November 7, 2014·3 min read

Researchers Identify New Genetic Cause of Epilepsy

A new study reports researchers have used whole genome sequencing to identify a new genetic cause of epileptic encephalopathy.

An image of fly spinal cord equivalent is shown.

Featured Neuroscience

·October 11, 2012·6 min read

Novel Mechanisms Underlying Major Childhood Neuromuscular Disease Identified

A study suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought. In a second study, the researchers identified the molecular pathway in SMA that leads to problems with motor function.