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Image shows a child standing under a street lamp alone

·September 23, 2019·4 min read

Perturbed genes regulating white blood cells linked to autism genetics and severity

Blood gene expression analysis uncovered a critical gene network that is disrupted in Autism. The disrupted gene network is related to fetal brain development and is also dysregulated in ASD cellular models. The findings provide further evidence that genetic factors influencing brain development during pregnancy are a primary cause of autism spectrum disorder.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 4, 2019·4 min read

New insight into motor neuron death mechanisms could be a step toward ALS treatment

When a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered.

Featured Genetics Neuroscience Open Neuroscience Articles

·February 6, 2019·3 min read

Nicotine Exposure During Pregnancy Alters Dopamine Neurons and Genes in Newborns

A new study reports chronic nicotine exposure during pregnancy alters the genetics and dopamine neurons of newborns. The findings could help researchers develop a possible cure for nicotine addiction.

This MRI scan image shows recurrent glioblastomas.

Brain Cancer Featured

·October 11, 2013·3 min read

Two-Drug Combination Slows Malignant Brain Tumors in Mice

A new study reports a novel combination of two targeted drugs dramatically slowed the growth of brain cancer tumors and significantly extended survival in mouse models.