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pediatric cancer

Brain Cancer Featured Neurology Neuroscience

·April 6, 2019·4 min read

New hope for treating childhood brain cancer

DIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells.

Image shows a brain scan from a cancer patient.

Brain Cancer Featured Neurology Open Neuroscience Articles

·September 28, 2017·8 min read

Study Splits Incurable Childhood Brain Tumors Into 10 New Diseases

Based on a large scale meta analysis, researchers report striking differences between children's high grade gliomas, so much so that they could be split into 10 different subtypes based on different characteristics. The findings have important implications for developing new and individualized treatments.

Image shows brain scan of a meningioma brain tumor.

Brain Cancer Featured Genetics Neuroscience Videos Open Neuroscience Articles

·August 6, 2017·4 min read

Mapping Mutations That Drive Tumors in Childhood Cancer Survivors

Researchers have identified a specific rearrangement involving the NF2 gene that appears to cause radiation induced meningiomas. The Nature Communication study reports this mutation could be a basis for why many long term pediatric cancer survivors go on to develop brain tumors later in life.