The neuropeptide somatostatin improves visual processing and cognitive behaviors by reducing excitatory inputs to parvalbumin-positive interneurons in mice.
Perineuronal nets (PNNs) and the neurons they enmesh can be damaged by poor diets. Excessive consumption of foods high in saturated fats and refined sugars cause inflammation and oxidative stress, resulting in cognitive decline and poor memory.
Optogenetic stimulation of parvalbumin cells resulted in a reduction of local blood flow and volume. The findings could shed new light on the neurobiological underpinnings of Alzheimer's disease and schizophrenia.
Researchers have identified a molecular mechanism which appears to be critical for the maturation of brain function, and may be used to restore plasticity in the aging brain.
A new study reveals the role synaptic feedback systems play in shaping learning processes. The findings could help develop more efficient artificial intelligence techniques.
Female mice who experienced early life stress developed problems and had fewer neurons in areas of the brain responsible for regulating emotions and making sense of rules, researchers report.
Researchers have mapped the relationship of two types of neurons implicated in psychiatric and movement disorder. The findings could lead to new treatments for a range of disorders from depression to Parkinson's disease.
Increasing fish consumption could help to lower the risk of developing Parkinson's and other neurodegenerative diseases, researchers report. The study reveals the protein parvalbumin can help to prevent the formation of alpha synuclein.