Severed axonal segments signal to Schwann cells to begin actin sphere formation and axon disintegration. If the process is disrupted, axon disintegration is slowed and axon fragments impair nerve regeneration.
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Researchers report polarized phosphorylation of shootin 1 within growth cones is required for the directional axon guidance induced by netrin-1 gradients.
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Researchers propose a new theory of memory formation, reporting memory storage does not rely on the strengthening of connection between memory cells, but on the pattern of connections that form within the first few minutes of an event.