Neurons in the infralimbic cortex control the link between food cues and behavioral actions, such as overeating or bad food choices. When these neurons are regulated, the rat models consumed fewer treats.
Findings define a connection between reward, dopamine, and circadian pathways in the overeating.
Prepronociceptin expressing neurons in the central amygdala become activated by consuming palatable foods. Reducing nociceptin making neurons in mice reduced binge eating when the animals had access to calorie-rich foods, without affecting the intake of ordinary dietary needs. The finding could help in the development of new therapies to combat obesity and binge eating.
Hippocampal dopamine 2 receptors, cells known to play a role in regulating memory, help curb the impulse to overeat.
Researchers have identified neurons in the brains of rats that control future food intake by preserving memories of past meals. The findings suggest boosting meal memories could help to manage overeating and curb obesity.
Researchers report mice fed a high fat diet produce an enzyme called MMP-2, which results in leptin being blocked from binding to its receptors. This, they report, prevents neurons from signaling that the stomach is full. The study suggests blocking MMP-2 may help people with obesity to lose weight.
A new study reveals a link between elevates microbiome levels of indole and hedonic eating. Researchers report those with higher levels of indole are more likely to have food addiction and overeating disorders.
A new study reports when certain brain areas react more strongly to food rewards than financial rewards, children are more likely to overeat, even if they are not hungry or overweight.
Researchers have discovered chemical circuits and mechanisms in the brain that separate food consumption from cravings.
New research sheds light on why images of enticing food affect us less when we are full.
Researchers have new evidence in rats to explain how it is that chocolate candies can be so completely irresistible. The urge to overeat such deliciously sweet and fatty treats traces to an unexpected part of the brain and its production of a natural, opium-like chemical.