Researchers report mice fed a high fat diet produce an enzyme called MMP-2, which results in leptin being blocked from binding to its receptors. This, they report, prevents neurons from signaling that the stomach is full. The study suggests blocking MMP-2 may help people with obesity to lose weight.
Researchers have discovered chemical circuits and mechanisms in the brain that separate food consumption from cravings.
Prepronociceptin expressing neurons in the central amygdala become activated by consuming palatable foods. Reducing nociceptin making neurons in mice reduced binge eating when the animals had access to calorie-rich foods, without affecting the intake of ordinary dietary needs. The finding could help in the development of new therapies to combat obesity and binge eating.
Researchers have identified neurons in the brains of rats that control future food intake by preserving memories of past meals. The findings suggest boosting meal memories could help to manage overeating and curb obesity.
A new study reports when certain brain areas react more strongly to food rewards than financial rewards, children are more likely to overeat, even if they are not hungry or overweight.
Researchers at Yale School of Medicine have zeroed in on a set of neurons in the part of the brain...
New research sheds light on why images of enticing food affect us less when we are full.
The absence of a specific type of neuron in the brain can lead to obesity and diabetes in mice report researchers. The outcome, however, depends on the type of diet that the animals are fed.
A new study reveals a link between elevates microbiome levels of indole and hedonic eating. Researchers report those with higher levels of indole are more likely to have food addiction and overeating disorders.
Neurons in the infralimbic cortex control the link between food cues and behavioral actions, such as overeating or bad food choices. When these neurons are regulated, the rat models consumed fewer treats.